Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

NKX3.1 localization to mitochondria suppresses prostate cancer initiation (Mouse 4M Prostate RNASeq)

ABSTRACT: NKX3.1 localization to mitochondria suppresses prostate cancer initiation (Mouse 4M Prostate RNASeq)

PROVIDER: PRJNA474606 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

NKX3.1 localization to mitochondria suppresses prostate cancer initiation (Mouse 4M Prostate RNASeq)

Project description:The NKX3.1 homeobox gene functions in mitochondria to regulate oxidative stress To investigate the role of NKX3.1 in regulation of oxidative stress, we employed transcriptome analysis of mouse prostate ( from 4 month old Nkx3.1+/+ and Nkx3.1-/- mice treated with paraquat), and human prostate cells ( RWPE1 cells engineered with empty vector (altered pTRIPZ), NKX3.1 wild type over-expression, and NKX3.1 (R52C) over-expression treated with paraquat). Mouse tissue or human cells were snap frozen for subsequent molecular analysis.

2021-04-13 | GSE115337 | GEO

NKX3.1 localization to mitochondria suppresses prostate cancer initiation

Project description:NKX3.1 localization to mitochondria suppresses prostate cancer initiation

| PRJNA474605 | ENA

NKX3.1 localization to mitochondria suppresses prostate cancer initiation (Human RWPE1 RNASeq)

2021-04-13 | GSE115335 | GEO

NKX3.1 localization to mitochondria suppresses prostate cancer initiation (Human RWPE1 RNASeq)

Project description:NKX3.1 localization to mitochondria suppresses prostate cancer initiation (Human RWPE1 RNASeq)

| PRJNA474603 | ENA

NKX3.1 Localization to Mitochondria Suppresses Prostate Cancer Initiation.

Project description: Not available

| S-EPMC7611624 | biostudies-literature

NKX3.1 localization to mitochondria suppresses prostate cancer initiation

Project description:This SuperSeries is composed of the SubSeries listed below.

2021-04-13 | GSE115338 | GEO

Identification of an NKX3.1-G9a-UTY regulatory network that controls prostate differentiation

Project description:To investigate the role of NKX3.1 in prostate differentiation, we employed transcriptome analysis of mouse seminal vesicle (from 15-month-old Nkx3.1+/+ mice); mouse prostate (from 4-month-old Nkx3.1+/+ and Nkx3.1-/- mice); human prostate cells (RWPE1 cells engineered with empty vector (altered pTRIPZ), NKX3.1 wild type over-expression, and NKX3.1 (T164A) mutant over-expression); and tissue recombinants (generated from combining engineered mouse epithelial cells (seminal vesicle epithelial cells or prostate epithelial cells from 2-month-old mice) and rat UGS mesenchymal cells). Mouse tissue or human cells were snap frozen for subsequent molecular analysis. This SuperSeries is composed of the SubSeries listed below.

2016-06-24 | GSE81440 | GEO

Identification of an NKX3.1-G9a-UTY regulatory network that controls prostate differentiation

2016-06-24 | E-GEOD-81440 | biostudies-arrayexpress

Identification of an NKX3.1-G9a-UTY regulatory network that controls prostate differentiation (Mouse_4M-Prostate_RNA-Seq)

Project description:Analysis of transcriptome of prostate tissue from 4-month-old Nkx3.1 +/+ and Nkx3.1 -/- mice. Total RNA obtained from prostate tissues from 4-month-old Nkx3.1 +/+ and Nkx3.1 -/- mice. Prostate tissues were harvested and processed for RNA isolation and transcriptome analysis using the MagMAX RNA isolation kit (Ambion).

2016-06-24 | E-GEOD-81424 | biostudies-arrayexpress

The cistrome of NKX3.1 in LNCaP prostate cancer cells

Project description:Here we report the genome-wide set of factors bound by NKX3.1 or control IgG in human prostate cancer cells (LNCaP). Examination of NKX3.1 binding in LNCaP prostate cancer cells

2013-08-21 | E-GEOD-40269 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data