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RNA-seq data from human SGBS adipocytes differentiated with marine oxohexadecenoic acids

ABSTRACT: RNA-seq data from human SGBS adipocytes differentiated with marine oxohexadecenoic acids

PROVIDER: PRJNA476151 | ENA |

REPOSITORIES: ENA

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RNA-seq data from human SGBS adipocytes differentiated with marine oxohexadecenoic acids

Project description:We recently isolated and identified (7E)-9-oxohexadec-7-enoic acid (1) and (10E)-9-oxohexadec-10-enoic acid (2) from the marine algae Chaetoceros karianus. Synthesis and biological characterization show that these are PPARα/γ dual agonists. Herein we report the gene expression data from human SGBS pre-adipocytes, stimulated to differentiate with 1, 2 or the classical PPARγ agonist rosiglitazone. The transcriptome analysis shows that both compounds induce anti-diabetic gene programs in adipocytes by upregulating insulin-sensitizing adipokines and repressing pro-inflammatory cytokines.

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Project description:To identify differentially expressed proteins in the secretome of differentiated SGBS cells human adipocytes) in response to iron.

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In situ promoter capture Hi-C data of differentiated SGBS human preadipocytes (days 0, 2, 8 and 16 of differentiation to adipocytes) and iPSC-derived hypothalamic neurons (days 12, 16 and 27 of differentiation)

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Expression data from human SGBS adipocytes under hypoxic conditions

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2011-04-14 | E-GEOD-28603 | biostudies-arrayexpress

Expression data from human SGBS adipocytes under hypoxic conditions

2011-04-14 | GSE28603 | GEO

Open chromatin profiling (ATAC-seq) of SGBS human preadipocytes (days 0, 2, 8 and 16 of differentiation to adipocytes) and iPSC-derived hypothalamic neurons (days 12, 16 and 27 of differentiation)

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