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Mapping replication domains using the Ion Torrent semiconductor sequencing platform [BrdU-IP]

ABSTRACT: Mapping replication domains using the Ion Torrent semiconductor sequencing platform [BrdU-IP]

PROVIDER: PRJNA476299 | ENA |

REPOSITORIES: ENA

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Mapping replication domains using the Ion Torrent semiconductor sequencing platform [BrdU-IP]

Project description:We show that semiconductor-based sequencing technology can be used to map mammalian replication domains, chromosomal units with similar DNA replication timing. Replicating DNA purified from mammalian cells was successfully sequenced by the Ion Torrent platform. The resultant replication domain map of mouse embryonic cells is comparable to those obtained by the conventional microarray-based method.

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Ion Torrent Sequencing Data March 2011

Project description:Ion Torrent Sequencing Data March 2011