Project description:The present study examines changes in global gene expression patterns and in virulence factor-associated genes in an extended spectrum beta-lactamase (ESBL)-producing UPEC (ESBL019) during the morphologic transitions induced by an ineffective antibiotic and in the presence of human primary bladder epithelial cells. The morphological shifts induced by ineffective antibiotics are associated with significant transcriptional virulence alterations in ESBL-producing UPEC, which may affect survival and persistence in the urinary tract.
Project description:Investigating the dissemination of extended-spectrum β-lactamase-resistant Salmonella spp. from agricultural to aquatic environments
Project description:Risk factors associated with Extended-Spectrum β-Lactamase Producing Enterobacterales Gut Colonization in Healthy Community Dogs in Israel
Project description:Local outbreak of extended spectrum beta lactamase SHV2a producing Pseudomonas aeruginosa reveals the emergence of a new specific sub-lineage of the international ST235 high risk clone