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Gene expression changes in THP1 cells at day 2 and 4 following shRNA knock-down of RUVBL2

ABSTRACT: Gene expression changes in THP1 cells at day 2 and 4 following shRNA knock-down of RUVBL2

PROVIDER: PRJNA481053 | ENA |

REPOSITORIES: ENA

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Expression analysis of THP1 cells following shRNA knock-down of RUVBL2

Project description:We used an inducible shRNA system and RNA-Seq to examine gene expression changes in acute myeloid leukemia THP1 cells following silencing of RUVBL2. RUVBL2 is a AAA+ ATPase that functions in a number of cellular processes, including chromatin remodeling and trnascriptional control, and is critical for survival of acute myeloid leukemia cells and in vivo disease progression.

2018-10-31 | GSE105253 | GEO

Gene expression changes in THP1 cells at day 2 and 4 following shRNA knock-down of RUVBL2

Project description:We used an inducible shRNA system and RNA-Seq to examine gene expression changes in acute myeloid leukemia THP1 cells following silencing of RUVBL2. RUVBL2 is a AAA+ ATPase that functions in a number of cellular processes, including chromatin remodeling and transcriptional control, and is critical for survival of acute myeloid leukemia cells and in vivo disease progression.

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Expression analysis of THP1 cells following shRNA knock-down of RUVBL2

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USP7 shRNA knock-down in T-ALL cells [Jurkat_HSB2_shRNA_RNA-seq]

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