Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Studies of modern Italian dog populations reveal multiple patterns for domestic breed evolution

ABSTRACT: Studies of modern Italian dog populations reveal multiple patterns for domestic breed evolution

PROVIDER: PRJNA495376 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Studies of modern Italian dog populations reveal multiple patterns for domestic breed evolution

Project description:Through thousands of years of breeding and strong human selection, the dog (Canis lupus familiaris) exists today within hundreds of closed populations throughout the world, each with defined phenotypes. A singular geographic region with broad diversity in dog breeds presents an interesting opportunity to observe potential mechanisms of breed formation. Italy claims 14 internationally recognized dog breeds, with numerous additional local varieties. To determine the relationship among Italian dog populations, we integrated genetic data from 263 dogs representing 23 closed dog populations from Italy, seven Apennine gray wolves. Using 142,840 genome-wide SNPs, this dataset was used in the identification of breed development routes for the Italian breeds that included divergence from common populations for a specific purpose, admixture of regional stock with that from other regions, and isolated selection of local stock with specific attributes.

2018-10-10 | GSE121027 | GEO

Studies of modern Italian dog populations reveal multiple patterns for domestic breed evolution.

Project description: Not available

| S-EPMC5838073 | biostudies-literature

Domestic dog lineages reveal genetic drivers of behavioral diversification

Project description:Selective breeding of domestic dogs has generated diverse breeds often optimized for performing specialized tasks. Despite the heritability of breed-typical behavioral traits, identification of causal loci has proven challenging due to the complexity of canine population structure. We overcome longstanding difficulties in identifying genetic drivers of canine behavior by developing an innovative framework for understanding relationships between breeds and the behaviors that define them utilizing genetic data for over 4,000 domestic, semi-feral and wild canids and behavioral survey data for over 46,000 dogs. We identify ten major canine genetic lineages and their behavioral correlates and show that breed diversification is predominantly driven by non-coding regulatory variation. We determine that lineage-associated genes converge in neurodevelopmental co-expression networks, identifying a sheepdog-associated enrichment for interrelated axon guidance functions. This work presents a scaffold for canine diversification that positions the domestic dog as an unparalleled system for revealing the genetic origins of behavioral diversity.

2022-12-07 | GSE213053 | GEO

Studies of canine breed development on the island of Sardinia recapitulate genomic features of human population isolates [MEDI]

Project description:The Italian island of Sardinia is well known in studies of human population isolates. It is also home to the Fonni's Dog, a breed of canine whose development was reliant on the functionality of the dog. Using genome-wide variant and sequence analyses, we have characterized the Fonni's Dog relative to 27 other dog breeds from the Mediterranean region. We determine introgression events relevant to Mediterranean breed development and describe how the Fonni's dog presents an intriguing model demonstrating the characteristics of traditional human population isolates and, in particular, exhibiting the unique demographic composition of the people of Sardinia.

2016-06-10 | GSE83154 | GEO

Studies of canine breed development on the island of Sardinia recapitulate genomic features of human population isolates [COO]

2016-06-10 | GSE83151 | GEO

Studies of canine breed development on the island of Sardinia recapitulate genomic features of human population isolates [CANE]

2016-06-10 | GSE83225 | GEO

Genomic analyses reveal the influence of geographic origin, migration and hybridization on modern dog breed development

Project description:Analysis of genotypes at 150,000 SNPs reveals patterns of allele and haplotype sharing that describes the breed relationships and development of 161 breeds of dog.

2017-03-17 | GSE96736 | GEO