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Gene expression in Jurkat T cell lines

ABSTRACT: Gene expression in Jurkat T cell lines

PROVIDER: PRJNA505417 | ENA |

REPOSITORIES: ENA

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Gene expression in Jurkat T cell lines

Project description:Jurkat cell lines were generated to stably express CD46 protein expressing either cytoplasmic tail 1 or 2 (BC1 or BC2). The transcription profile of these unactivated stable lines were compared with unactivated Jurkat cells.

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ATAC-seq analysis of Jurkat leukemia cell lines

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Gene expression of native Jurkat human leukemia cell line following 8h Brd4 inhibition by MMQO

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Glycine Chloramine directed gene expression changes in Jurkat T cell lines

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Gene expression of native Jurkat human leukemia cell line following 3h BET inhibition by MMQO or 3h HDAC inhibition by TSA

Project description:Basal Jurkat cell gene expression, MMQO or TSA treated Jurkat cell gene expression

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Effect of depletion of USF1 or USF2 on Jurkat Tat mHIV-Luciferase T cell gene expression.

Project description:To investigate the cooperative function USF factors for the regulation of T cell transcriptom, we established Jurkat mHIV-Luciferase cells in which USF1 or USF2 was knocked out by CRISPR-Cas9. We then performed gene expression profiling analysis using data obtained from RNA-seq of cell lines either left untreated or stimulated by PMA and Ionomycin co-treatment.

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role of miR-146a on Jurkat T cells

Project description:screenning the differentially expressed genes of Jurkat-FF3, Jurkat-miR146a, Jurkat-miR146a-sponge cell lines.

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Transcription profiling of human Jurkat-wt vs resistant Jurkat-A4 cell lines

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RNAi of human Jurkat cells knocked down LEDGF transcript of PSIP1 gene

Project description:The LEDGF transcript from the PSIP1 gene was knocked down in Jurkat cells using RNAi technology. The resulting Jurkat-derived cell line (Jurkat-siJK2) was compared to a control cell line (wild type Jurkat) using microarray analysis. Genes identified as being modulated by LEDGF were preferential targets of HIV integration. Experiment Overall Design: 2 cell lines were used, Jurkat-siJK2 (experimental) and wild-type Jurkat (control). 3 independent cultures of each cell line were used for independent RNA extractions, labeling reactions and array hybridizations.

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