Genomics

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Differentially expressed genes after miRNA or siRNA transfection in human cancer cell lines (T24, BOY, A549 and SK-MES)


ABSTRACT: Differentially expressed genes after miRNA or siRNA transfection in human cancer cell lines (T24, BOY, A549 and SK-MES)

PROVIDER: PRJNA508309 | ENA |

REPOSITORIES: ENA

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Publications

Aberrantly expressed PLOD1 promotes cancer aggressiveness in bladder cancer: a potential prognostic marker and therapeutic target.

Yamada Yasutaka Y   Kato Mayuko M   Arai Takayuki T   Sanada Hiroki H   Uchida Akifumi A   Misono Shunsuke S   Sakamoto Shinichi S   Komiya Akira A   Ichikawa Tomohiko T   Seki Naohiko N  

Molecular oncology 20190627 9


Bladder cancer (BC) is the ninth most malignant tumor worldwide. Some BC patients will develop muscle-invasive BC (MIBC), which has a 5-year survival rate of approximately 60% due to metastasis. As such, there is an urgent need for novel therapeutic and diagnostic targets for MIBC. Analysis of novel antitumor microRNA (miRNA)-mediated cancer networks is an effective strategy for exploring therapeutic targets and prognostic markers in cancers. Our previous miRNA analysis revealed that miR-140-5p  ...[more]

Publication: 1/2

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