Project description:Maternal methionine supply during late pregnancy can affect offspring growth and development via nutritional programming. In the present study, we investigated if increasing the supply of methionine during late-pregnancy in Holstein cows affects transcriptome profiles in the offspring.
Project description:Whole genome methylation of the daughters’ blood cells was assessed by Whole Genome Bisulfite Sequencing (WGBS), revealed the whole epigenetic landscape of calf blood cells, suggesting that the maternal metabolic status can indeed affect the embryo's epigenetic status and metabolic related pathways in offspring, providing further evidence for epigenetic intergenerational inheritance of metabolic stress in domestic animals
Project description:We assessed the transcriptomic adaptation of the calf rumen epithelium to changes in ruminal pH caused by feeding calf starter with and without forage during weaning transition.
