Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Mouse Gsr-null and TrxR1/Gsr-null liver transcriptomes

ABSTRACT: Mouse Gsr-null and TrxR1/Gsr-null liver transcriptomes

PROVIDER: PRJNA512020 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Mouse Gsr-null liver transcriptome

Project description:Mouse Gsr-null liver transcriptome

| PRJNA512022 | ENA

Mouse Gsr-null liver transcriptome

Project description:Genetic disruption of Gsr in mouse elicits only subtle changes in the liver transcriptome. Transcriptome analysis of Gsr-null livers was performed to further our understanding of pathways that may compensate for loss of Gsr, one of the two NADPH-dependent cytosolic disulfide reductases.

2019-05-01 | GSE124444 | GEO

Transcriptional profiling of mouse liver of PPARgamma null mice

Project description:Transcriptional profiling of mouse liver of PPARgamma null mice

| PRJNA735519 | ENA

AJS-ESI and nano-ESI source comparison and NPC1 differential liver proteome from NPC1 null mouse

Project description:AJS-ESI and nano-ESI source comparision of 2ug HeLa digest. Differential liver proteome via AJS-ESI of 11-wk NPC1 null mouse.

2018-08-30 | MSV000082874 | MassIVE

Metabolomics of the interaction between PPAR-alpha and age in the PPAR-alpha-null mouse (NMR assay)

Project description:Regulation between the fed and fasted state in mammals is partially controlled by peroxisome proliferator activated receptor-alpha (PPAR-alpha). Expression of the receptor is high in liver, heart and skeletal muscle, but decreases with age. A combined 1H NMR spectroscopy and GC-MS metabolomic approach has been used to examine metabolism in liver, heart, skeletal muscle and adipose tissue in PPAR-alpha null mice and wild type controls during ageing between 3-13 months. For the PPAR-alpha-null mouse multivariate statistics highlighted hepatic steatosis, reductions in the concentrations of glucose and glycogen in both liver and muscle tissue, and profound changes in lipid metabolism in each tissue, reflecting known expression targets of the PPAR-alpha receptor. Hepatic glycogen and glucose also decreased with age for both genotypes. These findings indicate the development of age related hepatic steatosis in the PPAR-alpha-null mouse, with the normal metabolic changes associated with ageing exacerbating changes associated with genotype. Furthermore, the combined metabolomic and multivariate statistics approach provides a robust method for examining the interaction between age and genotype. </p> The GC-MS assay for this study can be found in the MetaboLights study MTBLS314.

2018-10-11 | MTBLS261 | MetaboLights

Mouse Transcriptomes

Project description:Mouse Transcriptomes

| PRJEB2494 | ENA

RNA Sequencing analyses of control and HuD KO (Elavl4 null) mouse cortical transcriptomes

Project description:RNA Sequencing analyses of control and HuD KO (Elavl4 null) mouse cortical transcriptomes

| PRJNA714916 | ENA

Quantitative analysis of wild-type and Pgrmc1 knockout mouse liver transcriptomes

Project description:Quantitative analysis of wild-type and Pgrmc1 knockout mouse liver transcriptomes

| PRJNA729646 | ENA

Connexin43 null vs wildtype neonatal mouse HEART

Project description:Cy3-labeled cDNA obtained from four pools of three hearts of neonatal C57BL Cx43 null mice were compared to Cy3-labeled cDNA obtained from four pools of three hearts of neonatal C57BL wildtype mice through Cy5-labeled sample reference prepared at once for the entire experiment from aorta, brain, heart, kidney, liver, lung, ovary/testicles, spleen, and stomach - equal amounts from adult male and female C57BL mice. Keywords = Cx32 null vs wildtype neonatal mouse heart Keywords: parallel sample

2004-11-13 | GSE1961 | GEO

Transcriptome of LBR-null mouse kidneys

Project description:Transcriptome of LBR-null mouse kidneys

| PRJNA715765 | ENA