Dataset Information


SRNA sequencing of HDL from human donors

ABSTRACT: sRNA sequencing of HDL from human donors



Dataset's files

Action DRS
SRR8383430.fastq.gz Fastqsanger.gz
SRR8383431.fastq.gz Fastqsanger.gz
SRR8383432.fastq.gz Fastqsanger.gz
SRR8383433.fastq.gz Fastqsanger.gz
SRR8383434.fastq.gz Fastqsanger.gz
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Beta cell secretion of miR-375 to HDL is inversely associated with insulin secretion.

Sedgeman Leslie R LR   Beysen Carine C   Ramirez Solano Marisol A MA   Michell Danielle L DL   Sheng Quanhu Q   Zhao Shilin S   Turner Scott S   Linton MacRae F MF   Vickers Kasey C KC  

Scientific reports 20190307 1

Extracellular microRNAs (miRNAs) are a new class of biomarkers for cellular phenotypes and disease, and are bioactive signals within intercellular communication networks. Previously, we reported that miRNAs are secreted from macrophage to high-density lipoproteins (HDL) and delivered to recipient cells to regulate gene expression. Despite the potential importance of HDL-miRNAs, regulation of HDL-miRNA export from cells has not been fully studied. Here, we report that pancreatic islets and beta c  ...[more]

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