Project description:ERK is a key coordinator of the epithelial to mesenchymal transition (EMT). However, the mechanisms by which ERK controls the EMT program are not well understood. We used microarray to determine global changes of gene expression mediated by ERK2.
Project description:Interventions: Group 1: Quantitative Expression Analysis of the proteom and gene Expression of Primary Tumor, normal tissue, and metastases
Primary outcome(s): Disease associated Proteins and Genes
Study Design: Allocation: ; Masking: ; Control: ; Assignment: ; Study design purpose: basic science