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Single cell expression profiling of the mouse Sox17-null endocardium and myocardium at E8.5

ABSTRACT: Single cell expression profiling of the mouse Sox17-null endocardium and myocardium at E8.5

PROVIDER: PRJNA515853 | ENA |

REPOSITORIES: ENA

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Single cell expression profiling of the mouse Sox17-null endocardium at E8.5

Project description:To understand the function of Sox17 in the precursor cells of the mouse endocardium and the effect in the develoiping heart tube, single cell expression profiling of the Sox17-null endocardium and myocardium were performed.

2019-02-12 | GSE125321 | GEO

Single cell expression profiling of the mouse Sox17-null myocardium at E8.5

Project description:To understand the function of Sox17 in the precursor cells of the mouse endocardium amd the effect in the develoiping heart tube, single cell expression profiling of the Sox17-null endocardium and myocardium were performed.

2019-02-12 | GSE125322 | GEO

Single cell expression profiling of the mouse Sox17-null endocardium at E8.5

Project description:Single cell expression profiling of the mouse Sox17-null endocardium at E8.5

| PRJNA515855 | ENA

Single cell expression profiling of the mouse Sox17-null myocardium at E8.5

Project description:Single cell expression profiling of the mouse Sox17-null myocardium at E8.5

| PRJNA515854 | ENA

Single cell expression profiling of the mouse Sox17-null endocardium and myocardium at E8.5

Project description:This SuperSeries is composed of the SubSeries listed below.

2019-02-12 | GSE125323 | GEO

Transcriptome analysis identifies genes dysregulated in Sox7-null embryos at E8.5

Project description:To identify genes that are differentially expressed in the developing mouse embryo as a result of SOX7 deficiency, we performed bulk RNA-seq on Sox7-null and wild-type embryos harvested at E8.5.

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Endocardium differentiation through Sox17 expression in endocardium precursor cells regulates heart development in mice.

Project description: Not available

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Fz2-Fz7 double knock-out E8.5 mouse

Project description:Fz2Fz7 double knock out mouse microarray (E8.5)

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Transcriptional regulation of Sox17 in HUVEC

Project description:We identified Sox17 as a novel angiogenic transcription factor in the context of tumor. Our data revealed that Sox17 promotes tumor angiogenesis and tumor vessel abnormality. We found that Sox17 is specifically expressed in tumor endothelial cells within tumors. Our study elucidates a novel transcriptional regulation for tumor angiogenesis Control HUVECs vs. Sox17 knockdown HUVECs. Biological replicates: 3 control replicates, 3 transfected replicates.

2012-12-17 | E-GEOD-37395 | biostudies-arrayexpress

Whole transcriptome analysis of Sox17.Epi and Endo cells in mouse embryos

Project description:This experiment has been done to understand the dynamics of gene expression in Sox17.Epi and Endo cells using multiplex RNA-Seq technology. Sox17.Epi (Sox17^GFP+EpCAM+) and Sox17.Endo (Sox17^GFP+EpCAM-) cells were isolated by FACS from E9.5 mouse embryos. The spatial comparison between Sox17.Epi versus Sox17.Endo provides insight into which genes are differentially of specifically expressed in two populations.

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