Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

NCBI GEO Submission of human whole blood transcriptomes in response to a high-fat meal

ABSTRACT: NCBI GEO Submission of human whole blood transcriptomes in response to a high-fat meal

PROVIDER: PRJNA524902 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

NCBI GEO Submission of human whole blood transcriptomes in response to a high-fat meal

Project description:Modern humans spend most of their time having eaten recently. The purpose of the current project is to understand how the blood, which contains immune cells, responds in the hours after eating a meal that is moderately high in fat. We used a sequencing method to observe the expression of all the genes in blood cells in five participants who were each fed a high fat meal on three separate days. The results are reported in the manuscript, “Temporal changes in postprandial blood transcriptomes reveal subject-specific pattern of expression of innate immunity genes after a high-fat meal."

2019-03-01 | GSE127530 | GEO

Changes in Expression of Genes Regulating Airway Inflammation Following a High-Fat Mixed Meal in Asthmatics

Project description:Consumption of a high fat meal can increase neutrophilic airway inflammation in asthma. This study investigates the molecular mechanisms driving airway neutrophilia following a high fat meal in asthma.

2015-10-16 | GSE74075 | GEO

Transcriptional responses in 6.5 dpf larval zebrafish guts upon feeding a high-fat or low-fat meal

Project description:We report the transcriptional response of the zebrafish digestive organs to an acute high-fat feed using RNASeq analysis and highlight the changes in gene expression involved in the synthesis, storage, and dispersal of lipids. These key physiological responses to a high-fat meal all stem from the endoplasmic reticulum (ER), where lipids are formed and assigned to their fates.

2016-10-07 | GSE87704 | GEO

Transcriptomic changes in the duodenum mucosa after a high-fat (HF) or low-fat (LF) meal ingestion.

Project description:Fat intake is an important determinant in the development of obesity. The small intestine is the principal site of digestion and absorption of nutrients, and these short-term circulating nutrients and hormones as well as neural signals derived from the peripheral tissues in responses to a meal act at multiple central nervous system sites where food intake is controlled. In order to identify the HF-specific peripheral signals that can be therapeutic targets of obesity, we investigated transcriptomic changes in the duodenum mucosa after a HF or LF meal ingestion.

2017-11-26 | GSE59453 | GEO

O'Donovan2022 - the Mixed Meal Model

Project description:The Mixed Meal Model is a physiology based mathematical model describing the post-meal interplay between glucose, insulin, triglycerides and non-esterified fatty acids (NEFA).The Mixed Meal Model can be fit to meal response data by estimating nine model parameters from measured plasma glucose, insulin, triglyceride, and NEFA trajectories. These estimated model parameters have been shown to capture features of insulin resistance, beta-cell functionality, and liver fat accumulation from the meal response data.

2022-12-31 | MODEL2212300001 | BioModels

NCBI:txid939928

Project description:NCBI:txid939928 Raw sequence reads

| PRJNA633789 | ENA

EST SUBMISSION

Project description:EST SUBMISSION

| PRJEB22581 | ENA

Effects of temporal segmentation of meal composition on human adipose tissue transcriptome

Project description:There is few data about effects of temporal segmentation of meal composition on the metabolic response in humans. The meal-induced hormonal secretion in humans strongly depends on the meal composition and on the day time and may be involved in the circadian entrainment of metabolic gene expression. Our study investigated effects of two different diurnal patterns of meal composition (carbohydrate-rich meals in the morning and fat-rich meals in the evening or vice versa) on the gene expression in human subcutaneous adipose tissue (SAT).

2020-10-11 | GSE118280 | GEO

Iceman meal

Project description:The Iceman´s last meal consisted of fat, wild meat and cereals

| PRJEB26365 | ENA

Test of submission

Project description:Test of submission

| PRJEB30876 | ENA