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Mechanisms of heat-induced transcriptional memory profiled in mouse embryonic fibroblasts (MEFs).

ABSTRACT: Mechanisms of heat-induced transcriptional memory profiled in mouse embryonic fibroblasts (MEFs).

PROVIDER: PRJNA526631 | ENA |

REPOSITORIES: ENA

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Mechanisms of heat-induced transcriptional memory profiled in mouse embryonic fibroblasts (MEFs).

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Heat-induced transcriptional memory profiled in human K562 erythroleukemia cells.

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Project description:Heat-induced transcriptional memory profiled in human K562 erythroleukemia cells [PRO-seq]

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Chromatin accessibility in human K562 erythroleukemia cells profiled upon heat shock, recovery, and heat-induced transcriptional memory

Project description:Chromatin accessibility in human K562 erythroleukemia cells profiled upon heat shock, recovery, and heat-induced transcriptional memory

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Heat-induced transcriptional memory profiled in human K562 erythroleukemia cells.

Project description:Precision run-on sequencing (PRO-seq) of nascent RNA synthesis across the human genome. The PRO-seq data was generated from human K562 erythroleukemia cells that were either unconditioned (unCond) or preconditioned with multiple heat shock exposures (preCond). After two day recovery from the preconditioning, during which the cells underwent two mitotic divisions, the cells were additionally subjected to a single heat shock to measure nascent transcription in response to heat shock in unconditioned versus preconditioned cells.

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Project description:Heat-induced transgenerational memory of upregulated gene expression

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