Project description:Time-course systematic and quantitative analysis combining TiO2 enrichment and SILAC to investigate changes in the phosphoproteome of Ad2 and IMR-90 cells after adenovirus infection
Project description:Human mesenchymal stem cells are differentiated into osteoblasts in the presence or absence of ApoA-I treatment, the global gene profiles of MSCs with different time-points are compared. Day 0 is primary human MSCs without induction was used the baseline for comparision. We used microarrays to investigate the global gene expression profiles in hBM-MSCs with ApoA-I treatment for 1, 3, 5 days during osteogenesis