Bioreactor metagenome
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA531075 | ENA |
REPOSITORIES: ENA
Similar Datasets
Project description:aerobic granular sludge fermentation
| PRJNA300483 | ENA
Project description:Microbial diversity of aerobic granular sludge
| PRJNA269240 | ENA
Project description: Not available
| S-EPMC4661282 | biostudies-literature
Project description:Nitrogen removal characterization from a partial nitritation SBR operated under anoxic/aerobic phases treating mature landfill leachate
| PRJNA224134 | ENA
Project description:Improving phosphorus removal in aerobic granular sludge processes through selective microbial management
| PRJNA295902 | ENA
Project description: Not available
| S-EPMC6828613 | biostudies-literature
Project description:Impact of SRT on the Performance of Sequential Sulfate Reducing Anaerobic and Sulfide Oxidizing Aerobic Membrane Bioreactors Treating Textile Industry Wastewater
| PRJNA339930 | ENA
Project description:Subcutaneous implantation of cellulose sponges has been used for decades to induce vital granulation tissue formation. Illumina microarray was done in order to study the early gene expression in the granulation tissue formation.
2010-12-07 | GSE19749 | GEO
Project description:Proteinases play a pivotal role in wound healing by degrading molecular barriers, regulating cell-matrix interactions and availability of bioactive molecules. Matrix metalloproteinase-13 (MMP-13, collagenase-3) is a wide spectrum proteinase. Its expression and function is linked to the growth and invasion of many epithelial cancers such as squamous cell carcinoma. Moreover, the physiologic expression of MMP-13 is associated e.g. to scarless healing of human fetal skin and adult gingival wounds. While MMP-13 is not found in the normally healing skin wounds in human adults, it is expressed in mouse skin during wound healing. Thus, mouse wound healing models can be utilized for studying the role of MMP-13 in the events of wound healing. As the processes such as the migration and proliferation of keratinocytes, angiogenesis, inflammation and activation of fibroblasts are components of wound repair as well as of cancer, many results received from wound healing studies are also adaptable to cancer research. Classically, the process of wound healing can be devided into three phases which are histologically and functionally separate but temporally overlapping: 1) hemostasis and inflammation, 2) re-epithelialization and granulation tissue formation, and 3) matrix remodeling. Granulation tissue is formed into the wound via fibroplasia, angiogenesis and extracellular matrix (ECM) deposition by fibroblasts. Granulation tissue is rich in inflammatory cells, fibroblasts, myofibroblasts and blood vessels. After epidermal recovery, the granulation tissue is resolved via matrix remodeling and cell apoptosis. A sterile viscose cellulose sponge (VCS) characterized by defined size and structure can be used to experimentally induce formation of subcutaneous granulation tissue. Compared to normal granulation tissue, this model allows easy examination of the granulation tissue in its entirety but leaving out epidermal keratinocytes in the sample preparation. In this study, we studied the role of MMP-13 in the formation of mouse VCS-induced granulation tissue. We performed gene expression profiling of the granulation tissue samples of Mmp13-/- (KO) and wild type (WT) mice harvested at day 7, day 14 and day 21 after VCS implantation. Mmp13-/- (KO) mice were generated as described (Inada et al. 2004, PNAS, 101: 17192-17197) and used in these experiments after backcrossing at least seven generations into C57BL6 mice. The WT mice were generated from the backcrossed heterozygote Mmp13-/- (KO) mice. Granulation tissues were harvested at three time points (7d, 14d, 21d) from Mmp13-/- (KO) and WT mice. One sample of each mouse was analyzed (n=3, 7d; n=4, 14d; n=4, 21d; for each genotype). The samples were processed for RNA extraction and Affymetrix 3'IVT DNA microarray gene expression analysis.
2012-08-07 | E-GEOD-38822 | biostudies-arrayexpress