Genomics

Dataset Information

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Alternative splicing of LSD1+8a is mediated by SRRM4 in Neuroendocrine Prostate Cancer


ABSTRACT: Alternative splicing of LSD1+8a is mediated by SRRM4 in Neuroendocrine Prostate Cancer

PROVIDER: PRJNA545801 | ENA |

REPOSITORIES: ENA

Dataset's files

Source:
Action DRS
SRR9177600_1.fastq.gz Fastqsanger.gz
SRR9177600_2.fastq.gz Fastqsanger.gz
SRR9177591_1.fastq.gz Fastqsanger.gz
SRR9177591_2.fastq.gz Fastqsanger.gz
SRR9177601_1.fastq.gz Fastqsanger.gz
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Publications


Neuroendocrine prostate cancer (NEPC) is the most virulent form of prostate cancer. Importantly, our recent work examining metastatic biopsy samples demonstrates NEPC is increasing in frequency. In contrast to prostate adenocarcinomas that express a luminal gene expression program, NEPC tumors express a neuronal gene expression program. Despite this distinction, the diagnosis of NEPC is often challenging, demonstrating an urgent need to identify new biomarkers and therapeutic targets. Our prior  ...[more]

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