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TGFβ signaling in retinal tissue repair [Danio Rerio]

ABSTRACT: TGFβ signaling in retinal tissue repair [Danio Rerio]

PROVIDER: PRJNA546018 | ENA |

REPOSITORIES: ENA

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TGFβ signaling in retinal tissue repair [Danio Rerio]

Project description:In mammals, retinal damage is followed by Müller glia cell activation and proliferation. While retinal gliosis persists in adult mammals after an insult or disease, some vertebrates, including zebrafish, have the capacity to regenerate. We believe we are the first group to show that gliosis is a fibrotic-like process in mammals’ eyes caused by differential activation of canonical and non-canonical TGFβ signaling pathways.

2019-11-03 | GSE132141 | GEO

TGFβ signaling in retinal tissue repair

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TGFβ signaling in retinal tissue repair [Mus Musculus]

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Gene expression data from time course of fin regeneration in Danio rerio

Project description:This SuperSeries is composed of the following subset Series: GSE37163: Gene expression data from time course of fin regeneration in Danio rerio (part 1) GSE37164: Gene expression data from time course of fin regeneration in Danio rerio (part 2) Refer to individual Series

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Sequencing of Danio rerio liver for 2 age groups

Project description:Comparison of Danio rerio liver for 2 age groups treated with Rotenone. The RNA-seq data comprisess two age groups treated with Rotenone. Jena Centre for Systems Biology of Ageing - JenAge (www.jenage.de)

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Danio rerio cultivar:Danio rerio

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Sequencing of Danio rerio skin for 3 age groups

Project description:Comparison of temporal gene expression profiles from Danio rerio skin. The RNA-seq data comprise 3 age groups at 5, 24 and 30 months. Jena Centre for Systems Biology of Ageing - JenAge (www.jenage.de)

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Sequencing of Danio rerio skin for 2 age groups

Project description:Comparison of Danio rerio skin for 2 age groups treated with Rotenone. The RNA-seq data comprises two age groups treated with different Rotenone dose levels. Jena Centre for Systems Biology of Ageing - JenAge (www.jenage.de)

2021-10-19 | GSE102433 | GEO

Calsequestrins in skeletal and cardiac muscle from adult Danio rerio.

Project description:All vertebrates have multiple genes encoding for different CASQ isoforms. Increasing interest has been focused on mammalian and human CASQ genes since mutations of both cardiac (CASQ2) and skeletal (CASQ1) isoforms cause different, and sometime severe, human pathologies Danio rerio (zebrafish) is a powerful model for studying function and mutations of human proteins. In this work expression, biochemical properties and cellular and sub-cellular localization of Danio rerio native CASQ isoforms are investigated. By quantitative PCR three mRNAs were detected in skeletal muscle and one mRNA in heart. Three zebrafish CASQs were identified by mass spectrometry and they share properties with mammalian skeletal and cardiac CASQs. Skeletal calsequestrins were found primarily, but not exclusively, at the sarcomere Z-line level where Terminal Cisternae of Sarcoplasmic reticulum are located.

2015-11-10 | PXD002455 | Pride

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