Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

A Congenital Anemia Dissociates the Pleiotropic Functions of Master Transcription Factor GATA1

ABSTRACT: A Congenital Anemia Dissociates the Pleiotropic Functions of Master Transcription Factor GATA1

PROVIDER: PRJNA551420 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

A Congenital Anemia Dissociates the Pleiotropic Functions of Master Transcription Factor GATA1 [G1E_RNAseq]

Project description:A Congenital Anemia Dissociates the Pleiotropic Functions of Master Transcription Factor GATA1 [G1E_RNAseq]

| PRJNA551404 | ENA

A Congenital Anemia Dissociates the Pleiotropic Functions of Master Transcription Factor GATA1 [G1E_ATACseq]

Project description:A Congenital Anemia Dissociates the Pleiotropic Functions of Master Transcription Factor GATA1 [G1E_ATACseq]

| PRJNA551412 | ENA

A Congenital Anemia Dissociates the Pleiotropic Functions of Master Transcription Factor GATA1 [G1E_ChIPseq]

Project description:A Congenital Anemia Dissociates the Pleiotropic Functions of Master Transcription Factor GATA1 [G1E_ChIPseq]

| PRJNA551424 | ENA

A Congenital Anemia Dissociates the Pleiotropic Functions of Master Transcription Factor GATA1 [Patient_RNAseq]

Project description:A Congenital Anemia Dissociates the Pleiotropic Functions of Master Transcription Factor GATA1 [Patient_RNAseq]

| PRJNA551427 | ENA

A Congenital Anemia Dissociates the Pleiotropic Functions of Master Transcription Factor GATA1 [Patient_RNAseq]

Project description:Master regulators, such as the hematopoietic transcription factor GATA1, have numerous roles in lineage commitment and differentiation. While human GATA1 mutations result in several blood diseases, all characterized mutations act relatively early to impair hematopoietic differentiation. Here, we describe a distinct form of hemolytic anemia involving impaired terminal erythropoiesis with a reduced lifespan of circulating red blood cells. We show that this unique blood disorder results from mutations in a poorly characterized and intrinsically disordered C-terminal region of GATA1.

2021-12-31 | GSE133414 | GEO

A Congenital Anemia Dissociates the Pleiotropic Functions of Master Transcription Factor GATA1 [G1E_ChIPseq]

2021-12-31 | GSE133409 | GEO

A Congenital Anemia Dissociates the Pleiotropic Functions of Master Transcription Factor GATA1 [G1E_ATACseq]

2021-12-31 | GSE133404 | GEO

A Congenital Anemia Dissociates the Pleiotropic Functions of Master Transcription Factor GATA1 [G1E_RNAseq]

2021-12-31 | GSE133403 | GEO

A Congenital Anemia Dissociates the Pleiotropic Functions of Master Transcription Factor GATA1 [Beta-estradiol_RNAseq]

Project description:A Congenital Anemia Dissociates the Pleiotropic Functions of Master Transcription Factor GATA1 [Beta-estradiol_RNAseq]

| PRJNA551430 | ENA

A Congenital Anemia Dissociates the Pleiotropic Functions of Master Transcription Factor GATA1 [Beta-estradiol_RNAseq]

2021-12-31 | GSE133415 | GEO