Project description:The increasing spread of drug-resistant bacterial strains presents great challenges to clinical antibacterial treatment and public health, particularly with regard to β-lactamase-producing Enterobacteriaceae. A rapid and accurate detection method that can expedite precise clinical diagnosis and rational administration of antibiotics is urgently needed.
Project description:Conjunction of Modular Beta-lactamase Encoding Gene Amplification with Porin Loss Drives Carbapenem Resistance in ESBL Positive Enterobacteriaceae from Patients with Recurrent Bacteremia