Genomics

Dataset Information

2

Niche stiffness underlies the aging of CNS progenitor cells.


ABSTRACT: Niche stiffness underlies the aging of CNS progenitor cells.

PROVIDER: PRJNA552875 | ENA |

REPOSITORIES: ENA

Dataset's files

Source:
Action DRS
SRR9646940_1.fastq.gz Fastqsanger.gz
SRR9646940_2.fastq.gz Fastqsanger.gz
SRR9646950_1.fastq.gz Fastqsanger.gz
SRR9646950_2.fastq.gz Fastqsanger.gz
SRR9646941_1.fastq.gz Fastqsanger.gz
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Publications


Ageing causes a decline in tissue regeneration owing to a loss of function of adult stem cell and progenitor cell populations<sup>1</sup>. One example is the deterioration of the regenerative capacity of the widespread and abundant population of central nervous system (CNS) multipotent stem cells known as oligodendrocyte progenitor cells (OPCs)<sup>2</sup>. A relatively overlooked potential source of this loss of function is the stem cell 'niche'-a set of cell-extrinsic cues that include chemica  ...[more]

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