Ontology highlight
ABSTRACT:
PROVIDER: PRJNA555205 | ENA |
REPOSITORIES: ENA
Similar Datasets
Project description:This is the SIR model for disease spread of the Hong Kong flu in New York City in the late 1960's.
2022-01-27 | BIOMD0000001045 | BioModels
Project description:Here, we report genome sequences of the two bioluminescent S. aureus strains Xen31 and Xen36, obtained from PerkinElmer (#119242 and #119243, respectively). Xen31 was derived from the parental MRSA strain ATCC33591, a clinical strain isolated at Elmhurst Hospital in New York City. Xen36 was derived from parental strain ATCC 49525, a clinical isolate from a bacteremic patient. A copy of the modified luxABCDE operon from Photorhadbus luminescenst is integrated in the chromosome of Xen31 and in a native plasmid of Xen36.
2022-12-14 | E-MTAB-12210 | biostudies-arrayexpress
Project description:ddRAD reads for New York City brown rats (Rattus norvegicus)
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Project description:Study Design: The Cancer Alliance study was a collaboration of nine academic medical institutions in the New York city area and led by the New York Genome Center. Tumor-normal paired samples were submitted by the institutions for whole genome, whole exome and transcriptome sequencing and bioinformatics analysis at New York Genome Center. Relevant clinical histories were also collected. Raw sequence files were available to all collaborators. Variant call files were analyzed both manually by interpreters at NYGC and by IBM Watson Genome Analytics. This study was approved by a central institutional review board (IRB), Biomedical Research Alliance of New York, and by local IRBs, including Stony Brook University and Northwell Health. The study was supported in part by a grant from the IBM corporation (IBM Watson Health) to the New York Genome Center, New York Genome Center philanthropic funds and Rockefeller University grant # UL1TR000043 from the National Center for Advancing Translational Sciences (NCATS), and the National Institutes of Health (NIH) Clinical and Translational Science Award (CTSA) program. The principal investigator Robert B. Darnell MD, PhD., is a Howard Hughes Medical Institute Investigator.
Results: Pending Publication of Analysis of Study
Conclusions: Pending Publication of Analysis of Study
| EGAS00001004013 | EGA
Project description:Ulcerative colitis is a chronic inflammatory disorder for which a definitive cure is still missing. This is characterized by an overwhelming inflammatory milieu in the colonic tract where a composite set of immune and non-immune cells orchestrate its pathogenesis. Over the last years, a growing body of evidence has been pinpointing gut virome dysbiosis as underlying its progression. Nonetheless, its role during the early phases of chronic inflammation is far from being fully defined. Here we show the gut virome-associated Hepatitis B virus protein X, most likely acquired after an event of zoonotic spillover, to be associated with the early stages of ulcerative colitis and to induce colonic inflammation in mice. It acts as a transcriptional regulator in epithelial cells, provoking barrier leakage and altering mucosal immunity at the level of both innate and adaptive immunity. This study paves the way to the comprehension of the aetiopathogenesis of intestinal inflammation and encourages further investigations of the virome as a trigger also in other scenarios. Moreover, it provides a brand-new standpoint that looks at the virome as a target for tailored treatments, blocking the early phases of chronic inflammation and possibly leading to better disease management.
2023-02-20 | GSE204665 | GEO
Project description:Gastrointestinal microbiota of wild and inbred house mouse
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