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Transcriptional control of influenza-specific CD4+ tissue-resident memory T cell generation

ABSTRACT: Transcriptional control of influenza-specific CD4+ tissue-resident memory T cell generation

PROVIDER: PRJNA565358 | ENA |

REPOSITORIES: ENA

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Transcriptional control of influenza-specific CD4+ tissue-resident memory T cell generation

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CD69+ memory T lymphocytes of the bone marrow and spleen express the signature transcripts of tissue-resident memory T lymphocytes

Project description:To understand tissue resident features of memory CD4+ and CD8+ T lymphocytes of the bone marrow and/or spleen according to expressing or not the tissue retention marker CD69, we performed whole transcriptome profiling of ex vivo antigen-specific CD69+ and CD69- memory CD4+ T cells isolated from bone marrow and spleen, and ex vivo CD69+ and CD69- memory CD8+ T cells isolated from bone marrow.

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