Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Epigenome analysis of glioma patient surgical samples and corresponding xenotransplants and cell lines

ABSTRACT: Epigenome analysis of glioma patient surgical samples and corresponding xenotransplants and cell lines

PROVIDER: PRJNA573660 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Epigenome analysis of glioma patient surgical samples and corresponding xenotransplants and cell lines

Project description:Genome wide DNA methylation profiling of glioma patient surgical samples and corresponding xenotransplants and cell lines. The Illumina Infinium 450k Human DNA methylation Beadchip and the Illumina EPIC Beadchip were used to obtain DNA methylation profiles. Samples include 22 patient surgical samples, 26 xenografted patient tumors, and 6 cell lines derived there-of.

2020-10-01 | GSE137845 | GEO

Epigenome analysis of pediatric glioma

Project description:Epigenome analysis of pediatric glioma

| PRJNA557182 | ENA

Characterizing the epigenome of glioma stem cells

Project description:Characterizing the epigenome of glioma stem cells

| PRJNA357621 | ENA

Expression data from human glioma tissues and corresponding adjacent non-tumor tissues

Project description:We performed microarray expression profiling to analyze the differentially expressed genes between 5 human glioma tissues and corresponding adjacent non-tumor tissues.

2022-09-16 | GSE209547 | GEO

Expression data from human glioma tissues and corresponding adjacent non-tumor tissues

Project description:We performed microarray expression profiling to analyze the differentially expressed genes between 19 human glioma tissues and corresponding adjacent non-tumor tissues.

2022-01-26 | GSE188256 | GEO

FFPE-samples from cavitational ultrasonic surgical aspirates are suitable for RNA profiling of gliomas

Project description:During surgical procedures of gliomas, tissular material obtained from cavitational ultrasonic surgical aspirators (CUSAs) is generally discarded but can exceed amount and quality of certain tumour core resections (TCRs). From archived FFPE-samples, we compared the profiles of somatic mutations and gene expression in the solid material from aspirates and TCRs obtained from the same patients in selected gliomas encompassing grade II to IV. Despite the characteristic heterogeneity of gliomas, we found substantial similarities between the corresponding aspirates and TCRs that included mutations used in the clinical routine and glioma-associated transcriptional signatures. Based on these results, we confirmed the suitability of CUSA-fixed biomaterial from glioma surgeries for downstream applications.

2021-10-20 | GSE166696 | GEO

Intronic natural antisense transcripts in glioma patient biopsies

Project description:Natural non-coding antisense transcripts (ncNATs) are long non-coding RNAs (lncRNA) transcribed from the opposite strand of a separate protein coding or non-coding gene and can affect the overlapped gene expression through epigenetic, transcriptional, post-transcriptional and/or translational modulations. ncNATs can influence cancerous cell proliferation, migration and therapeutic resistance. Recently, growing numbers of ncNATs were shown to be dysregulated in cancerous cells, however, actual impact of ncNATs on cancer progression remains largely unknown. We performed RNA-seq on post-surgical tumor samples from 26 glioma patients, and normal brain tissue.

2023-02-24 | GSE219250 | GEO

Analysis of tumor cell RNA (glioma and melanoma) and their corresponding microvesicles

Project description:Primary glioblastoma cells and primary malignant melanoma cells were grown in vitro (less than 15 passages). Exosomes/microvesicles were isolated from the media supernatant at the same time as RNA was extracted from the cells. The goal of the study was to compare the gene expression profiles in exosomes/microvesicles compared to the cells that release them. Analysis of tumor cell RNA (glioma and melanoma) and their corresponding microvesicles.

2012-01-31 | E-GEOD-35444 | biostudies-arrayexpress

Expression data from glioblastoma surgical specimens

Project description:Surgical resection is the first choice of the standardized treatment scheme for glioblastoma and is performed under general anesthesia. Previous researches have shown that propofol and sevoflurane have different effects on the biological process of glioma cells from the molecular level. Some of them, for instance, control the glioma cell proliferation, invasion and migration In vitro or In vivo. We used mRNA microarray to discuss the effects of propofol and sevoflurane on gene expression in patients with glioblastoma. The correlation between DEGs and patients’ prognosis was further analyzed.

2021-06-28 | GSE179004 | GEO

Expression data from human glioma tissues and corresponding adjacent non-tumor tissues

Project description:Expression data from human glioma tissues and corresponding adjacent non-tumor tissues

| PRJNA778739 | ENA