Project description:Gene expression profiling reveals a potential role of TCQA in the upregulation of hair pigmentation in mice hair shaft Skin was isolated from mice dorsal part treated with MilliQ and TCQA; Microarray gene expression profiling was conducted.
Project description:Murine GVH-SSc dorsal scapular skin samples were analyzed to determine the effect of IFNAR-1 inhibition on gene expression at day 14 and day 28. Gene expression in GVH-SSc skin from mice treated with a neutralizing IFNAR-1 antibody was compared to that in GVH-SSc skin from mice treated with isotype IgG, with skin from syngeneic graft controls as reference.