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Streptomyces clavuligerus strain:ATCC 27064 | isolate:Leon (Spain)

ABSTRACT: Streptomyces clavuligerus strain:ATCC 27064 | isolate:Leon (Spain) Genome sequencing

PROVIDER: PRJNA579405 | ENA |

REPOSITORIES: ENA

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Transcriptional analysis between Streptomyces clavuligerus ATCC 27064 and a mutant altered in antibiotic production

Project description:The objective was to analyze the differential expression between the wild strain and the Streptomyces clavuligerus ΔclaR::aac mutant Six experimental conditions were assayed, two strains (Streptomyces clavuligerus ATCC 27064, S. clavuligerus ΔclaR::aac) in three culture times (22.5h, 46.5h and 60 h). Two biological replicates for each condition.

2015-08-05 | E-GEOD-66683 | biostudies-arrayexpress

Transcriptional analysis between Streptomyces clavuligerus ATCC 27064 and mutants altered in the antibiotics production

Project description:The objective is to analyze the differential expression between the wild strain and a ccaR-deleted and oppA2::aph mutants 6 biological conditions were used, three strains in two times (exponential and stationary growth phase; Streptomyces clavuligerus ATCC 27064, S. clavuligerus M-bM-^HM-^FccaR and S. clavuligerus oppA2::aph). Four biological replicates were made for each condition

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Streptomyces clavuligerus strain:ATCC 27064

Project description:Streptomyces clavuligerus ATCC 27064 genome sequencing project

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Expression data from Streptomyces clavuligerus

Project description:To increase production of the important pharmaceutical compounds, both mutagenesis approaches and rational engineering have been extensively applied. Mutagenesis approaches are most popular in industry, but their effects have not yet been studied very well. Here, we used microarrays to compare the transcriptomes of the S. clavuligerus wild type (ATCC 27064) strain and the DS48802 clavulanic acid high-producer strain, which has been obtained by classical strain improvement (mutagenesis). Streptomyces clavuligerus strains were grown in shake flasks. RNA was extracted after 70h and hybridized to microarrays.

2010-11-10 | E-GEOD-24033 | biostudies-arrayexpress

Transcriptional analysis between Streptomyces clavuligerus ATCC 27064 and a mutant altered in antibiotic production

Project description:The objective was to analyze the differential expression between the wild strain and the Streptomyces clavuligerus ΔclaR::aac mutant

2015-08-05 | GSE66683 | GEO

Expression data from Streptomyces clavuligerus

2010-11-10 | GSE24033 | GEO

Transcriptional analysis between Streptomyces clavuligerus ATCC 27064 and a pSCL4- S. clavuligerus mutant

Project description:The objective is to analyze the differential expression between the wild strain and a pSCL4- S. clavuligerus mutant Experiment type Expression profiling by array

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Primary transcriptome and translatome analysis determines transcriptional and translational regulatory elements encoded in the Streptomyces clavuligerus genome

Project description:We obtained the high-quality genome sequence of S. clavuligerus ATCC 27064, and determined genome-wide TSSs. Then, RNA-Seq and ribosome profiling were additionally exploited to reveal fundamental regulatory elements for transcription and translation.

2019-05-16 | GSE128216 | GEO

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