Genomics

Dataset Information

0

Non-canonical base modifications of bacterial origin in a eukaryotic genome [MeDIP-seq]


ABSTRACT: Non-canonical base modifications of bacterial origin in a eukaryotic genome [MeDIP-seq]

PROVIDER: PRJNA588094 | ENA |

REPOSITORIES: ENA

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1
altmetric image

Publications

Bacterial N4-methylcytosine as an epigenetic mark in eukaryotic DNA.

Rodriguez Fernando F   Yushenova Irina A IA   DiCorpo Daniel D   Arkhipova Irina R IR  

Nature communications 20220228 1


DNA modifications are used to regulate gene expression and defend against invading genetic elements. In eukaryotes, modifications predominantly involve C5-methylcytosine (5mC) and occasionally N6-methyladenine (6mA), while bacteria frequently use N4-methylcytosine (4mC) in addition to 5mC and 6mA. Here we report that 4mC can serve as an epigenetic mark in eukaryotes. Bdelloid rotifers, tiny freshwater invertebrates with transposon-poor genomes rich in foreign genes, lack canonical eukaryotic C5-  ...[more]

Similar Datasets

2022-01-07 | GSE140050 | GEO
2022-01-07 | GSE140049 | GEO
2022-01-07 | GSE140051 | GEO
| PRJNA588087 | ENA
| PRJNA588092 | ENA
| PRJNA588089 | ENA
2022-01-07 | GSE140052 | GEO
| S-EPMC6847078 | BioStudies
| S-EPMC140540 | BioStudies
| S-EPMC3074620 | BioStudies