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Expression analysis of microRNA in malignant peritoneal mesothelioma induced by intraperitoneal injections of iron saccarate in rats

ABSTRACT: Expression analysis of microRNA in malignant peritoneal mesothelioma induced by intraperitoneal injections of iron saccarate in rats

PROVIDER: PRJNA589522 | ENA |

REPOSITORIES: ENA

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Expression analysis of microRNA in malignant peritoneal mesothelioma induced by intraperitoneal injections of iron saccarate in rats

Project description:Iron plays an important role in oxidative tissue damage and subsequent carcinogenesis. Iron deposition in the peritoneum causes neoplastic changes. Here we used microRNA (miR) microarrays in a rat model by repeated intraperitoneal injections of ferric saccharate. miR microarray revealed the miR-199/214 as a distinctive feature of sarcomatoid mesothelioma.

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Transcriptome analysis of mesothelial cells induced by intraperitoneal injections of crocidolite in rats

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Project description:Intraperitoneal injection of crocidolite initiates malignant peritoneal mesothelioma (MM) in mice. We performed high-resolution comparative genomic hybridization to identify characterstics in the genomic profiles of crocidolite-induced MM in the mice.

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