Project description:The role of PDK1 on mammary tumorigenesis and its interaction with PPARdelta, was assessed. Transgenic mice were generated in which PDK1 was expressed in the mammary epithelium. We used microarrays to analyse global gene expression changes in MMTV-PDK1 transgenic mice versus wild-type mice and determine any differential responses to GW501516 treatment. RNA was isolated (RNeasy Mini Kit, Qiagen) from mammary gland tissue from nulliparious transgenic and wild-type mice maintained on normal rodent chow or a diet supplemented with GW501516 for 1 week.

2011-02-05 | E-GEOD-27083 | biostudies-arrayexpress

Gene expression by TRPS1 knocked down in T47D

Project description:Gene expression by TRPS1 knocked down in T47D

| PRJNA408130 | ENA

Gene expression by BTF3 knocked down in Vcap cells

Project description:Gene expression by BTF3 knocked down in Vcap cells

| PRJNA506234 | ENA

Expression data from SIX1 knocked-down HKc/DR cells

Project description:Expression data from SIX1 knocked-down HKc/DR cells

| PRJNA523785 | ENA

Gene expression by LASP1 knocked down in PC3 cells

Project description:Gene expression by LASP1 knocked down in PC3 cells

| PRJNA655418 | ENA

Expression data from H157 non-small cell lung carcinoma cells with and without DJ-1 expression knocked-down

Project description:DJ-1 expression protects H157 cells from cell death, using siRNA oligomers we knocked down DJ-1 and evaulated gene expression using Affymetrix U133A GeneChip arrays. Keywords: siRNA comparison

2006-10-01 | GSE5519 | GEO

Hydrogen Deuterium Exchange of PDK1

Project description:This project consisted of three HDX-MS experiments. First, we compared the dimeric PDK1(SKD-PIF) to monomeric PDK1(SKD) and mapped the differences in deuterium incorporation onto the dimer model. We then compared the deuterium incorporation kinetics for the kinase (PDK1(SKD)) and PH (PDK1(PH) domains of PDK1 with full-length PDK1 (PDK1(FL)) in pairwise experiments.

2022-05-20 | PXD027401 | Pride

Gene expression of S100A10 knocked down human breast cancer cells

Project description:Gene expression of S100A10 knocked down human breast cancer cells

| PRJNA661489 | ENA