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Transcriptional profiling of pyramidal neurons in the cerebral cortex of Glt25d2-TRAP (DU9) mice administered either saline or cocaine [TRAP-seq]

ABSTRACT: Transcriptional profiling of pyramidal neurons in the cerebral cortex of Glt25d2-TRAP (DU9) mice administered either saline or cocaine [TRAP-seq]

PROVIDER: PRJNA593189 | ENA |

REPOSITORIES: ENA

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Transcriptional profiling of pyramidal neurons in the cerebral cortex of Glt25d2-TRAP (DU9) mice administered either saline or cocaine [TRAP-seq]

Project description:TRAP translational profiling is a method that allows investigators to genetically characterize specific cell types in complex tissues such as mouse brain. Using this technique we obtained RNA-Seq data from actively translating transcripts present in pyramidal neurons in the cerebral cortex of adult Glt25d2-EGFP/Rpl10a (DU9) mice that were administered either saline or cocaine.

2019-12-16 | GSE141337 | GEO

Transcriptional profiling of neurons in the cerebral cortex of S100a10-TRAP (ES691) mice administered either saline or cocaine

Project description:TRAP translational profiling is a method that allows investigators to genetically characterize specific cell types in complex tissues such as mouse brain. Using this technique we obtained RNA-Seq data from actively translating transcripts present in pyramidal neurons in the cerebral cortex of adult S100a10-EGFP/Rpl10a (ES691) mice that were administered either saline or cocaine.

2019-12-16 | GSE141464 | GEO

Transcriptional profiling of neurons in the striatum of Chat-TRAP (DW167) mice administered either saline or cocaine

Project description:TRAP translational profiling is a method that allows investigators to genetically characterize specific cell types in complex tissues such as mouse brain. Using this technique we obtained RNA-Seq data from actively translating transcripts present in neurons in the striatum of adult Chat-EGFP/Rpl10a (DW167) mice that were administered either saline or cocaine.

2019-12-16 | GSE141204 | GEO

Transcriptional profiling of medium spiny neurons in the striatum of Drd2-TRAP (CP101) mice administered either saline or cocaine

Project description:TRAP translational profiling is a method that allows investigators to genetically characterize specific cell types in complex tissues such as mouse brain. Using this technique we obtained RNA-Seq data from actively translating transcripts present in medium spiny neurons in the whole striatum of adult Drd2-EGFP/Rpl10a (CP101) mice that were administered either saline or cocaine.

2019-12-16 | GSE141463 | GEO

Transcriptional profiling of medium spiny neurons in the striatum of Drd1-TRAP (CP73) mice administered either saline or cocaine

Project description:TRAP translational profiling is a method that allows investigators to genetically characterize specific cell types in complex tissues such as mouse brain. Using this technique we obtained RNA-Seq data from actively translating transcripts present in medium spiny neurons in the whole striatum of adult Drd1-EGFP/Rpl10a (CP73) mice that were administered either saline or cocaine.

2019-12-16 | GSE141424 | GEO

Transcriptional profiling of neurons in the cerebral cortex of S100a10-TRAP (ES691) mice administered either saline or cocaine

Project description:Transcriptional profiling of neurons in the cerebral cortex of S100a10-TRAP (ES691) mice administered either saline or cocaine

| PRJNA593554 | ENA

Transcription profiling of mouse hippocampus after maternal treatment with saline or 20 mg/kg cocaine twice daily on gestational days 8-19

Project description:We explored the hypothesis that maternal cocaine exposure could alter the fetal epigenetic machinery sufficiently to cause lasting neurochemical and functional changes in the offspring. These data were used as preliminary results for paper:; Maternal cocaine administration in mice alters DNA methylation and gene expression in hippocampal neurons of neonatal and prepubertal offspring. Svetlana I. Novikova, Fang He, Jie Bai, Nicholas J. Cutrufello, Ashiwel S. Undieh and Michael S. Lidow Experiment Overall Design: Pregnant CD1 mice were administered either saline or 20 mg/kg cocaine twice daily on gestational days 8-19. Male pups from each of ten litters of the cocaine and control groups were analyzed at 3 (P3) day postnatum. Pyramidal layer tissue from the right hemisphere of one of these brains (On every section, the pyramidal layer, encompassing the C1, C2 and C3 hippocampal regions, was carefully cut out)was used for analyzing gene expression. Laser microdissection was performed on a Leica ASLMD laser capture microdissection system (Leica Microsystems, Wetzlar, Germany).

2008-06-15 | E-GEOD-6651 | biostudies-arrayexpress

Transcriptional profiling of neurons in the striatum of Chat-TRAP (DW167) mice administered either saline or cocaine

Project description:Transcriptional profiling of neurons in the striatum of Chat-TRAP (DW167) mice administered either saline or cocaine

| PRJNA592568 | ENA

Transcriptional profiling of pyramidal neurons in the cerebral cortex of a Htr4-TRAP (ES1299) mouse line

2019-12-13 | GSE141921 | GEO

Transcriptional profiling of medium spiny neurons in the striatum of Drd2-TRAP (CP101) mice administered either saline or cocaine

Project description:Transcriptional profiling of medium spiny neurons in the striatum of Drd2-TRAP (CP101) mice administered either saline or cocaine

| PRJNA593555 | ENA

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