Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Genomic analysis of ketoconazole resistance in the dandruff-associated cutaneous yeast Malassezia restricta.

ABSTRACT: Genomic analysis of ketoconazole resistance in the dandruff-associated cutaneous yeast Malassezia restricta.

PROVIDER: PRJNA593855 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Genomic analysis of ketoconazole resistance in the dandruff-associated cutaneous yeast Malassezia restricta.

Project description:To understand ketoconazole resistance mechanism in M. restricta, we investigated differentially expressed genes in the azole resistant isolates using transcriptome profile. Transcriptomes of ketoconazole susceptible and resistant M. restricta cells in the absence and precence of ketoconazole were compared and analyzed by RNA sequencing.

2020-12-05 | GSE141548 | GEO

Understanding the Mechanism of Action of the Anti-Dandruff Agent Zinc Pyrithione against Malassezia restricta.

Project description:Purpose: Understanding the Mechanism of Action of the Anti-Dandruff Agent Zinc Pyrithione against Malassezia restricta. Methods: The transcriptome profile of the ZPT-treated M. restricta cells compared to that of untreated cells were generated by RNA-Seq using Illumina HiSeq. Generated raw reads that passed quality filters were mapped to the reference genome. Mapped reads were counted by featureCounts in Subread package v1.4.3 and the relative transcript abundance was TPM-normalized. Results: A number of genes were differentially expressed in the ZPT-treated cells, which include genes involved in zinc transporter, mitochondirial function, TCA cycle, electron transport chain and lipase.

2018-12-25 | GSE112036 | GEO

The genomic tandem quadruplication is associated with ketoconazole resistance of Malassezia pachydermatis

Project description:Purpose: Understanding the ketoconazole resistance mechanism in Malassezia pachydermatis Methods: The transcriptome profile of the ketoconazole resistant M. pachydermatis KCTC 27587 cells compared to that of ketoconazole sensitive M. pachydermatis CBS 1879 cells were generated by RNA-Seq using Illumina HiSeq. Results: The expressions of genes in the region of quadruplicated chromosome 4 were up-regulated.

2019-02-07 | GSE118354 | GEO

Malassezia restricta strain:KCTC 27527

Project description:Malassezia restricta KCTC 27527

| PRJNA270302 | ENA

Malassezia restricta CBS 7877

Project description:Malassezia restricta CBS 7877 genome, complete sequence

| PRJNA474956 | ENA

Malassezia restricta strain:KCTC 27527

Project description:Malassezia restricta strain:KCTC 27527 Genome sequencing

| PRJNA477735 | ENA

Comparative Analysis of Antifungal Mechanism of Lauryl betaine in the Human Fungal Pathogens Cryptococcus neoformans and Malassezia restricta

Project description:Purpose: Understanding the mechanism of action of lauryl betaine against Cryptococcus neoformans and Malassezia restricta. Methods: The transcriptome profile of the lauryl betaine-treated cells compared to that of untreated cells were generated by RNA-seq Illumina Hiseq. Results: A number of genes were differentially expressed in the lauryl betaine-treated cells, which include genes involved in ergosterol biosynthetic pathway.

2019-08-22 | GSE124734 | GEO

Malassezia restricta

Project description:Fungus associated with some skin disorders, including seborrheic dermatitis and dandruff

| PRJNA18725 | ENA

Understanding the Mechanism of Action of the Anti-Dandruff Agent Zinc Pyrithione against Malassezia restricta.

Project description:Understanding the Mechanism of Action of the Anti-Dandruff Agent Zinc Pyrithione against Malassezia restricta.

| PRJNA438989 | ENA