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Transcriptional profiles in pregnant women in response to vaccination

ABSTRACT: Transcriptional profiles in pregnant women in response to vaccination

PROVIDER: PRJNA603999 | ENA |

REPOSITORIES: ENA

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Transcriptional profiles in pregnant women in response to vaccination

Project description:Vaccination in pregnancy is an effective tool to protect both the mother and infant. Vaccines against tetanus, pertussis and influenza are recommended for use in pregnancy and new vaccines with specific indications for pregnancy are in the clinical trials pipeline. However our understanding of the immune response to vaccination in pregnancy is incomplete. We compared the effect of pregnancy on early (24 hours) transcriptional responses to vaccination. Pregnant mice and women were immunised with Boostrix-IPV, a vaccine containing pertussis antigens.

2020-01-31 | GSE144540 | GEO

Blood gene expression profiles following influenza vaccination in pregnant women

Project description:Blood gene expression profiles following influenza vaccination in pregnant women

| PRJNA701250 | ENA

Blood gene expression profiles following influenza vaccination in pregnant women

Project description:Influenza immunization during pregnancy provides protection to the mother and the infant. Studies in adults and children with inactivated influenza vaccine (IIV) have identified changes in immune gene expression that correlated with antibody responses. We studied changes in transcriptional profiles induced by IIV in pregnant women and to identify correlates of antibody responses.

2021-02-11 | GSE166545 | GEO

Transcriptional profiling of mRNAs from peripheral blood mononuclear cells of healthy pregnant women hpw

Project description:The oligo micoarrays were used to determine gene expression profiles of peripheral blood mononuclear cells of healthy pregnant women.<br><br>

2013-10-30 | E-MEXP-3969 | biostudies-arrayexpress

vaginal microbiome for pregnant women

Project description:vaginal microbiome for pregnant women

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vaginal microbiota of pregnant women

Project description:vaginal microbiota of pregnant women

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Transcriptional profiling of mRNAs from pooled peripheral blood mononuclear cells of healthy pregnant women pool_hpw.

Project description:The oligo micoarrays were used to determine gene expression profiles of pooled total RNA isolated from peripheral blood mononuclear cells of healthy pregnant women.

2013-09-22 | E-MEXP-3964 | biostudies-arrayexpress

Proteomes of Placenta from Pregnant Women with Intrahepatic Cholestasis of Pregnancy

Project description:The iTRAQ analysis combined with liquid chromatography-tandem mass spectrometry (LC-MS/MS) was performed to separate differentially expressed placental proteins from 4 pregnant women with ICP and 4 healthy pregnant women.

2021-09-24 | PXD028734 | Pride

Transcriptional responses in muscle of pregnant mouse upon immunization

2020-01-25 | GSE144218 | GEO

Analysis of plasma proteome of pregnant women with polycystic ovary syndrome (PCOS

Project description:Polycystic ovary syndrome (PCOS) is the most common endocrinological disorder of fertile-aged women. PCOS has been associated with adverse pregnancy outcomes and abnormalities of the placenta. By taking a quantitative label-free quantitative proteomics approach we set out to investigate if changes in the plasma proteome of pregnant women with PCOS could elucidate the mechanisms behind the pathologies observed in PCOS pregnancies. We have performed label-free quantitative proteomics on plasma samples from pregnant women with PCOS at term (n=14) and plasma samples from pregnant control women (n = 23) matched for age, gestational length and BMI. The samples are derived from BASIC pregnancy cohort from Uppsala, Sweden. A total of 169 proteins with two or more unique peptides were identified.

2019-11-25 | PXD012034 | Pride

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