Genomics

Dataset Information

299

Leucoraja erinacea


ABSTRACT: Leucoraja erinacea genome sequencing project

ORGANISM(S): Leucoraja erinacea  

PROVIDER: PRJNA60893 | ENA |

REPOSITORIES: ENA

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Publications

A natural deletion of the HoxC cluster in elasmobranch fishes.

King Benjamin L BL   Gillis J Andrew JA   Carlisle Heather R HR   Dahn Randall D RD  

Science (New York, N.Y.) 20111201 6062


Hox proteins are a metazoan-specific family of transcription factors that are required for developmental patterning. The genomic arrangement of Hox genes into four paralogous clusters is a primitive feature of jawed vertebrates. By using high-throughput sequencing, we demonstrate the absence of all HoxC transcripts from embryos of the shark Scyliorhinus canicula and the skate Leucoraja erinacea and the absence of all HoxC genes and two HoxC-associated microRNAs from the genome of L. erinacea. Th  ...[more]

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