Dataset Information


Neisseria meningitidis NZ-05/33

ABSTRACT: Neisseria meningitidis NZ-05/33 Genome sequencing project

ORGANISM(S): Neisseria meningitidis NZ-05/33  



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Neisseria meningitidis is structured in clades associated with restriction modification systems that modulate homologous recombination.

Budroni Sonia S   Siena Emilio E   Dunning Hotopp Julie C JC   Seib Kate L KL   Serruto Davide D   Nofroni Chiara C   Comanducci Maurizio M   Riley David R DR   Daugherty Sean C SC   Angiuoli Samuel V SV   Covacci Antonello A   Pizza Mariagrazia M   Rappuoli Rino R   Moxon E Richard ER   Tettelin Hervé H   Medini Duccio D  

Proceedings of the National Academy of Sciences of the United States of America 20110228 11

Molecular data on a limited number of chromosomal loci have shown that the population of Neisseria meningitidis (Nm), a deadly human pathogen, is structured in distinct lineages. Given that the Nm population undergoes substantial recombination, the mechanisms resulting in the evolution of these lineages, their persistence in time, and the implications for the pathogenicity of the bacterium are not yet completely understood. Based on whole-genome sequencing, we show that Nm is structured in phylo  ...[more]

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