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CircularRNA Sequencing of HPV16 positive cervical cancer tissues, HSIL tissues and normal cervical epithelial tissues

ABSTRACT: circularRNA Sequencing of HPV16 positive cervical cancer tissues, HSIL tissues and normal cervical epithelial tissues

PROVIDER: PRJNA612785 | ENA |

REPOSITORIES: ENA

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circularRNA Sequencing of HPV16 positive cervical cancer tissues, HSIL tissues and normal cervical epithelial tissues

Project description:To explore the circRNA expression profiles during the development and progression of cervical cancer, we performed RNA sequencing analysis with ribosomal RNA-depleted in HPV negative normal cervical epithelium, HPV16 positive normal cervical epithelium, HPV16 positive high-grade squamous intraepithelial lesion (HSIL), and HPV16 positive cervical squamous cell carcinoma tissues,6 cases in each group.Totally 66868 circRNAs were identified (Back-spliced junctions reads≥1)

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Expression data of mRNA and circRNA from HPV16 positive cervical cancer tissues, HSIL tissues and normal cervical epithelial tissues

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Expression data of mRNA and circRNA from HPV16 positive cervical cancer tissues, HSIL tissues and normal cervical epithelial tissues

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The expression profile analysis of lncRNAs and mRNAs for cervical cancer

Project description:To further explore the expression profile of lncRNAs and mRNAs in cervical cancer, six cases of HPV-positive cervical cancer tissues (including three HPV16 and three HPV18 positive patients) and three HPV-negative normal cervical tissues were collected randomly that were confirmed by histopathological. These patients did not accept any local or systemic treatment.

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