Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Plasma protein-profiling to predict distant metastasis in locoregionally advanced nasopharyngeal carcinoma (LA-NPC)

ABSTRACT: Plasma protein-profiling to predict distant metastasis in locoregionally advanced nasopharyngeal carcinoma (LA-NPC)

PROVIDER: PRJNA629317 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Plasma protein-profiling to predict distant metastasis in locoregionally advanced nasopharyngeal carcinoma (LA-NPC)

Project description:Plasma protein expression patterns can be used as prognostic biomarkers in various types of cancer. We aimed to identify a protein-based signature for distant metastatic risk assessment in patients with locoregionally advanced nasopharyngeal carcinoma (LA-NPC).

2020-09-02 | GSE149587 | GEO

LncRNA expression-profiling to predict distant metastasis in locoregionally advanced nasopharyngeal carcinoma

Project description:LncRNAs can be used as prognostic biomarkers in various types of cancer. We aimed to identify a lncRNA expression pattern for individual distant metastatic risk assessment in patients with locoregionally advanced nasopharyngeal carcinoma (LA-NPC).

2022-04-10 | GSE180272 | GEO

Gene expression-profiling to predict distant metastasis in locoregionally advanced nasopharyngeal carcinoma

Project description:Gene expression patterns can be used as prognostic biomarkers in various types of cancer. We aimed to identify a gene expression pattern for individual distant metastatic risk assessment in patients with locoregionally advanced nasopharyngeal carcinoma (LA-NPC).

2019-05-02 | GSE103611 | GEO

Gene expression-profiling to predict induction chemotherapy efficacy in locoregionally advanced nasopharyngeal carcinoma

Project description:Gene expression signature can be used to predict treatment efficacy in various types of tumour. We aim to identify a gene expression signature to predict efficacy of induction chemotherapy (IC) in patients with locoregionally advanced nasopharyngeal carcinoma (LA-NPC).

2021-04-14 | GSE132112 | GEO

CircRNA expression-profiling to predict prognosis in locoregionally advanced nasopharyngeal carcinoma

Project description:CircRNAs serve as prognostic biomarkers in various types of cancer. We aimed to identify a circRNA signature for individual relapse risk assessment in patients with locoregionally advanced nasopharyngeal carcinoma (LA-NPC).

2023-12-21 | GSE190271 | GEO

LncRNA expression-profiling to predict distant metastasis in locoregionally advanced nasopharyngeal carcinoma

Project description:LncRNA expression-profiling to predict distant metastasis in locoregionally advanced nasopharyngeal carcinoma

| PRJNA747297 | ENA

Comparison of protein profiles in the serum of NPC patients with different prognosis by high-throughput protein microarrays

Project description:High levels of c-Src in serum of patients with NPC was independent prognostic indicators for poor outcome of patients. In this study, eight NPC patients with or without distant metastasis, followed up more than five years, was used to acquire protein profiles in serum to find out serum biomarkers to predict outcome in NPC patients.

2015-05-12 | E-GEOD-68764 | biostudies-arrayexpress

Comparision of La-RNA-binding between wild type La and sumoylation deficient La mutant (K41/200R) in HEK293 cells.

Project description:We performed a RNA immunoprecipitations experiments using gfp-specific antibodies to precipitate gfp-tagged La proteins from from gfp-La wild type and sumoylation deficient La mutant (K41/200R) cells and found that specific mRNAs are preferentially enriched gfp-La wild type RIPs when compared to sumoylation deficient La mutant (K41/200R) RIPs.

2017-11-22 | GSE102842 | GEO

mRNA expression profiling of ebv-miR-BART7-expressing NPC cells

Project description:Nasopharyngeal carcinoma (NPC) is endemic in Southeast Asia and southern China. The primary treatment for NPC is radiotherapy. Despite of the encouraging results of radiotherapy, local recurrence or distant metastases of NPC after the initial therapy is frequently found due to radioresistance. Therefore, there is an urgent need to identify genes that control radiosensitivty, aiming to reduce disease recurrence. Epstein-Barr virus (EBV) infection was closely associated with undifferentiated NPC. EBV-encoded microRNAs (miRNAs) played crucial roles in the pathogenesis of NPC. Ebv-miR-BART7 belongs to the 44 EBV BART miRNAs and was found to be up-regulated in NPC tissues and plasma. Forced expression of ebv-miR-BART7 enhanced the radiosensitivity of NPC cells. However, the mechanisms underlying the sensitizing effect of ebv-miR-BART7 on radiation remain largely unknown. Given that miRNA exerts biological functions by regulating its targets, we used microarray to identify the targets of ebv-miR-BART7 that regulate radiosensitivity of NPC cells.

2017-03-31 | GSE79571 | GEO

RNA-Seq quantitative analysis of the regulation of platelet-derived extracellular vesicles on NPC cells transcriptomes

Project description:Nasopharyngeal carcinoma (NPC) is a malignant epithelial tumor with a high metastatic feature and invasive nature. The survival rate of NPC patients is still very low due to the high incidence of distant metastasis. Platelets are versatile blood cells and mediate the distant metastasis of tumor cells via the blood circulation. However, the role and underlying mechanism of platelets responsible for the NPC cells hematogenous metastasis are not well understood. In our study, we found that platelet-derived EVs of NPC patients (P-EVs) induced the metastasis and mesenchymal-epithelial transition process in NPC cells. To shed light on the mechanism underlying P-EVs-induced NPC metastasis and MET process, we performed high throughput RNA-Seq analyses to reveal the differentially expressed genes in NPC cells treated with or without P-EVs. We observed that there was a significant overlap in the expression of integrins that were altered in 6-10B and 5-8F upon P-EVs treatment. Of these, integrin β3 (ITGB3) exhibited the most obvious upregulation.

2022-02-23 | GSE196879 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data