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Hepatic transcriptomic alterations for bis(2-ethylhexyl) tetrabromophthalate (TBPH) after 5-day exposure in rats

ABSTRACT: Hepatic transcriptomic alterations for bis(2-ethylhexyl) tetrabromophthalate (TBPH) after 5-day exposure in rats

PROVIDER: PRJNA642238 | ENA |

REPOSITORIES: ENA

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Hepatic transcriptomic alterations for bis(2-ethylhexyl) tetrabromophthalate (TBPH) after 5-day exposure in rats

Project description:To identify liver transcripts differentially expressed due to treatment with bis(2-ethylhexyl) tetrabromophthalate (TBPH), we collected RNA from male Harlan Sprague Dawley rats exposed to 0, 0.07, 0.71, 7.06, 70.6 or 706 mg/kg TBPH, 5 days after exposure for animals 7 weeks of age. These samples were interrogated with the Affymetrix Rat Genome 230 2.0 GeneChip array. A total of 0,0,0,0, and 0 gene transcripts were differentially expressed due to TBPH treatment after exposure to 0.07, 0.71, 7.06, 70.6 or 706 mg/kg TBPH (false discovery rate (FDR) < 0.05).

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Toxicogenomic Screen of Replacements for bis(2-ethylhexyl) phthalate (DEHP) Using the Immortalized TM4 Sertoli Cell Line

2015-08-06 | E-GEOD-66812 | biostudies-arrayexpress

Hepatic transcriptomic alterations for 1,2-bis(tribromophenoxy)ethane (BTBPE) (Firemaster 680) after 5-day exposure in rats

Project description:Hepatic transcriptomic alterations for 1,2-bis(tribromophenoxy)ethane (BTBPE) (Firemaster 680) after 5-day exposure in rats

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Hepatic transcriptomic alterations for tetrabromobisphenol A-bis(2,3-dibromopropyl ether) (TBBPA-DBPE) after 5-day exposure in rats

Project description:Hepatic transcriptomic alterations for tetrabromobisphenol A-bis(2,3-dibromopropyl ether) (TBBPA-DBPE) after 5-day exposure in rats

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