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Transciptomic analysis of human aortic smooth muscle cells (HASMCs) with BAF60a overexpression

ABSTRACT: Transciptomic analysis of human aortic smooth muscle cells (HASMCs) with BAF60a overexpression

PROVIDER: PRJNA642742 | ENA |

REPOSITORIES: ENA

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Transciptomic analysis of human aortic smooth muscle cells (HASMCs) with BAF60a overexpression

Project description:We used NGS-derived transcriptome profiling (RNA-seq) to compare the transcriptional difference between human aortic smooth muscle cells (HASMCs) infected with 20MOI adenovirus encoding human BAF60a (AdBAF60a) or GFP (AdGFP)

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Transciptomic analysis of human aortic smooth muscle cells (HASMCs) with BAF60a knockdown

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Transciptomic analysis of human aortic smooth muscle cells (HASMCs) with BAF60a knockdown

Project description:Transciptomic analysis of human aortic smooth muscle cells (HASMCs) with BAF60a knockdown

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The tRNA derived fragments (tRFs) expression profiles in human aortic smooth muscle cells (HASMCs)

Project description:To explore the potential involvement of tRNA derived fragments (tRFs) in the human aortic vascular smooth muscle cells (HASMCs), we conducted tRFs profiling in three pairs of differentiated HASMCs (treated with PBS) and dedifferentiated HASMCs (treated with PDGF-BB 50 ng/ml) by microarray. Our results showed that tRFs were aberrantly expressed in dedifferentiated HASMCs compared with differentiated HASMCs and provided potential targets for novel insights into VSMC differentiation or vascular remodeling diseases.

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Identity transcript factor EB (TFEB) target genes in human aortic smooth muscle cells (HASMCs)

Project description:Identity transcript factor EB (TFEB) target genes in human aortic smooth muscle cells (HASMCs)

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Allele-specific 4C-seq of rs2836411 located in the ERG gene in HUVEC and HASMCs

Project description:Allele-specific circular chromosome conformation capture sequencing (4C-seq) using the single nucleotide polymorphism rs2836411 as a bait was performed in two cell types: human umibilical vein endothelial cells (HUVECs) and human aortic smooth muscle cells (HASMCs).

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