Project description:This study aimed to identify differential expression of miRNAs in hepatocellular carcinoma patient tissues and explore the function of miRNAs acting as sponge of circRNAs.
Project description:This study aimed to identify differential expression of lncRNAs and mRNAs in hepatocellular carcinoma patient tissues and potential regulation of mRNAs by lncRNAs.
Project description:Arraystar Human circRNA Microarray is designed for the global profiling of human circRNAs. In this study, we applied a circRNA microarray to screen the potential biomarker for HCC. 20 samples extracted from plasma samples including HCC group before operation, and after operation, CH group and control group. Each group contained five samples.
Project description:mRNA/ lncRNA/ circRNA profiles of hepatocellular carcinoma and the adjacent tissues were generated by deep sequencing using Illumina NovaSeq 6000.
Project description:Hepatocellular carcinoma (HCC) is currently the third leading cause of death worldwide and the most common type of primary liver cancer, finding noninvasive biomarkers for HCC diagnostic and prognostic are very urging. Previous genomic studies mainly focus on finding miRNA biomarkers for HCC. In this study, we focus on finding circRNA fragments suitable for serving as hcc biomarkers with plasma exosomal RNA-seq..