Project description:ChIP-seq for H3K27ac or H3K9ac was performed in different platinum sensitive and resistant epithelial ovarian cancer cell lines and in sensitive A2780 cells with shRNA induced knockdown of MBD3.
Project description:Analysis of a panel of 41 human ovarian cancer cell lines for the study of ovarian cancer biology, drug response and drug sensitivity.
Project description:Genome wide DNA methylation profiling of ovarian cancer cell lines and normal cells. The Illumina Infinium 27k Human DNA methylation Beadchip was used to obtain DNA methylation profiles for approximately 27,000 CpGs. Samples included 46 ovarian cancer cell lines, 4 normal counterparts and 8 controls.
Project description:We used microarrays to assess gene expression in proliferating ovarian cancer cell lines Ovarian cancer cell lines were plated and harvested when 50-80% confluent. RNA was extracted and hybridized on Affymetrix microarrays. At least 3 biological repeats were performed for each cell line.
