Project description:Primary objectives: The primary objective is to investigate circulating tumor DNA (ctDNA) via deep sequencing for mutation detection and by whole genome sequencing for copy number analyses before start (baseline) with regorafenib and at defined time points during administration of regorafenib for treatment efficacy in colorectal cancer patients in terms of overall survival (OS).
Primary endpoints: circulating tumor DNA (ctDNA) via deep sequencing for mutation detection and by whole genome sequencing for copy number analyses before start (baseline) with regorafenib and at defined time points during administration of regorafenib for treatment efficacy in colorectal cancer patients in terms of overall survival (OS).
Project description:We used the Illumina RNAseq approach to study the effects of acute exposure to elevated CO2 on gene expression in primary polyps of Acropora millepora Examination of transcriptome in Acropora millepora primary polyps at 380, 750 and 1000 ppm CO2 after 3 days exposure
Project description:We compared the effect of acute (Moya et al 2012) and chronic exposure to elevated pCO2 on gene expression in primary polyps of Acropora millepora Examination of transcriptome in Acropora millepora primary polyps at 380 and 750 ppm CO2 (air) after 9 days exposure
Project description:We compared the effect of acute (Moya et al 2012) and chronic exposure to elevated pCO2 on gene expression in primary polyps of Acropora millepora
Project description:We used the Illumina RNAseq approach to study the effects of acute exposure to elevated CO2 on gene expression in primary polyps of Acropora millepora
