Project description:In Mycobacterium tuberculosis, the PhoPR two-component regulatory system controls production and secretion of proteins and lipid virulence effectors. Several mutations, present in phoR of Mycobacterium canettii relative to M. tuberculosis, impact the expression of the PhoP regulon and the pathogenicity of the strains. Here, we analyse by RNA-seq the expression profile of PhoP-regulated genes between the two M. tuberculosis strains H37Rv and HN878 and the two M. canettii isolates STB-Ks and STB-Kr.

2023-05-24 | GSE229680 | GEO

Mycobacterium canettii strain:NLA000701671

Project description:Mycobacterium canettii strain:NLA000701671 Genome sequencing

| PRJNA625554 | ENA

Mycobacterium canettii CIPT 140010059

Project description:Mycobacterium canettii CIPT 140010059 genome sequencing

| PRJEA68135 | ENA

<i>Mycobacterium canettii</i> Infection of Adipose Tissues.

Project description: Not available

| S-EPMC5434109 | biostudies-literature

Ready Experimental Translocation of Mycobacterium canettii Yields Pulmonary Tuberculosis.

Project description: Not available

| S-EPMC5695119 | biostudies-literature

Impact of mutations in rv2887, putative transcriptional repressor, on gene expression in Mycobacterium tuberculosis.

Project description:This study was aimed towards understanding the consequences of mutating rv2887, a putative transcriptional repressor, on gene expression in Mycobacterium tuberculosis. Since clones carrying mutations in this gene were found to be highly resistant to a potent mycobactericidal compound, 14, we also tested the impact of short-term exposure to this compound on gene expression in Mycobacterium tuberculosis.

2016-07-01 | GSE77556 | GEO

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