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Single-cell RNAsequencing of the ventral rhombomere 1 of the developing mouse [INDROPS]

ABSTRACT: Single-cell RNAsequencing of the ventral rhombomere 1 of the developing mouse [INDROPS]

PROVIDER: PRJNA663554 | ENA |

REPOSITORIES: ENA

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Single-cell RNAsequencing of the ventral rhombomere 1 of the developing mouse [INDROPS]

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Project description:During development, rhombomere 1 gives rise to a multitude of cell types, including serotonergic as well as glutamatergic neurons that populate the raphe nuclei. Transcription factor Gata2 has been shown to regulate the development of the serotonergic neurons in the rhombomere 1. To further understand the role and targets of Gata2 in the rhombomere 1 during development, we used cDNA microarrays to compare gene expression in the embryonic day 12.5 (E12.5) rhombomere 1 tissues extracted from wild-type and Gata2 mutant embryos.

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