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Redundant mechanisms driven independently by RUNX1 and GATA2 for hematopoietic development

ABSTRACT: Redundant mechanisms driven independently by RUNX1 and GATA2 for hematopoietic development

PROVIDER: PRJNA663959 | ENA |

REPOSITORIES: ENA

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Redundant mechanisms driven independently by RUNX1 and GATA2 for hematopoietic development

Project description:Redundant mechanisms driven independently by RUNX1 and GATA2 for hematopoietic development

| PRJNA663960 | ENA

Redundant mechanisms driven independently by RUNX1 and GATA2 for hematopoietic development

Project description:Redundant mechanisms driven independently by RUNX1 and GATA2 for hematopoietic development

| PRJNA663961 | ENA

Redundant mechanisms driven independently by RUNX1 and GATA2 for hematopoietic development

Project description:Redundant mechanisms driven independently by RUNX1 and GATA2 for hematopoietic development

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Redundant mechanisms driven independently by RUNX1 and GATA2 for hematopoietic development [zebrafish bulk RNA-seq2]

Project description:Redundant mechanisms driven independently by RUNX1 and GATA2 for hematopoietic development [zebrafish bulk RNA-seq2]

| PRJNA717672 | ENA

Redundant mechanisms driven independently by RUNX1 and GATA2 for hematopoietic development

Project description:Here we used RNA sequencing to characterize the transcriptional profile of the kidney of runx1 knock out zebrafish adult compared to wild type.

2022-01-14 | GSE158098 | GEO

Redundant mechanisms driven independently by RUNX1 and GATA2 for hematopoietic development

Project description:Here we used RNA sequencing to characterize the transcriptional profile of the total RNA from c-Kit+ cells of Runx1 KO and control mice.

2022-01-14 | GSE158100 | GEO

Redundant mechanisms driven independently by RUNX1 and GATA2 for hematopoietic development

Project description:We used single cell-RNA sequencing to investigate the expression and the heterogeneity of wild type and runx1-mutant cd41-GFPLow cd41GFP hematopoietic stem and progenitor cells at embryonic (2.5 days post fertilization, dpf) and larval stages (6, 10 16 dpf).

2022-01-14 | GSE158099 | GEO

Redundant mechanisms driven independently by RUNX1 and GATA2 for hematopoietic development [zebrafish bulk RNA-seq2]

Project description:Here we used RNAsequencing to characterize the transcriptional profile of the kidney of runx1 knock out zebrafish adult compared to wild type.

2022-01-14 | GSE169689 | GEO

Redundant mechanisms driven independently by RUNX1 and GATA2 for hematopoietic development

Project description:This SuperSeries is composed of the SubSeries listed below.

2022-01-14 | GSE158101 | GEO

Genome-wide analysis of GATA1, GATA2, RUNX1, FLI1 and SCL binding in primary human megakaryocytes

Project description:We have mapped the binding sites for the five key regulators GATA1, GATA2, RUNX1, FLI1 and TAL1/SCL in primary human megakaryocytes. Statistical analysis identified subsets of enriched as well as depleted combinatorial binding patterns. In particular simultaneous binding by all 5 factors was highly enriched and occurred in the vicinity of many genes known to be involved in blood and megakaryocyte development. Knock down in zebrafish of 8 of these genes with no previously known role in hematopoiesis, revealed all to be essential for thrombocyte and/or erythroid development. Combinatorial analysis of multi-factor ChIP-Seq datasets coupled with a high-throughput in vivo screen therefore offers a powerful strategy to identify novel essential regulators of complex mammalian differentiation processes. 5 transcription factors and rabbit-IgG in megakaryocytes.

2011-06-01 | E-GEOD-24674 | biostudies-arrayexpress

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