Project description:Chronic hepatitis B (CHB) is a huge health burden in China, tongue diagnosis is the premise of personalized treatment of CHB by traditional Chinese medicine(TCM). The modern biological interpretation of pathological TCM tongue coating manifestation is unclear We performed transcriptional analysis in CHB patients with white tongue coating(WTC) or yellow tongue coating(YTC) to explain the potential inner biological differences
Project description:Potentilla indica and Melastoma dodecandrum lour are medicinal herbs used in traditional Chinese medicine. We sampled the plants from Nanyang Technological University's herb garden for transcriptomics analysis.
Project description:To identify biomarkers regulated by traditional Chinese medicine Astragalus membranaceus Fischer Bge. var. mongolicus Bge. Hsiao in colorectal cancer. We have identified several differentially expressed genes including microRNAs using Affymetrix HTA-2.0 array. In this dataset, we include the expression data obtained from colon cancer cell line HCT116 grafted into nude mice. The mice was treated either water or traditional Chinese medicine Astragalus membranaceus for 28 days. These data are used to obtain 1425 genes that are differentially expressed in response to Astragalus membranaceus treatment.
Project description:In the study, patients with type 2 diabetes with obesity and hyperlipidemia were treated by traditional Chinese medicine Jiangtang Tiaozhi Prescription of 24 weeks, we chosed 6 effective cases, 6 invalid cases and 6 health people as control to analysis the molecular mechanism of TCM treatment. According to the research of LncRNA microarray, GO analysis, Pathway analysis, we found out the target LncRNAs, as well as their associated mRNAs were contribute to the good outcome of Jiangtang Tiaozhi Formula. Then we expand to 12 cases in each group for qPCR validation.
Project description:The goals of the study are to compare differently expressed genes in heart tissues of acute Myocardial Infarction mice with control mice and idetify the targets of Traditional Chinese Medicine HXP.
