Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNA-sequencing data for 923 enhancer deletion newborn mouse whole skin

ABSTRACT: RNA-sequencing data for 923 enhancer deletion newborn mouse whole skin

PROVIDER: PRJNA667132 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

923 enhancer deletion newborn mouse

Project description:923 enhancer deletion newborn mouse

| PRJNA667049 | ENA

RNA-sequencing data for 923 enhancer deletion newborn mouse whole skin

Project description:We examined the RNA expression profiles of whole skin from newborn CRISPR-edited mice that have the 923 enhancer located within the Epidermial Differentiation Complex deleted. We examined two independent deletion lines, 923del and 923large, both homozygous mutants and heterozygotes, as well as wild type mice and involucrin Ivl knockout mice. We find that Ivl, the gene most proximal to 923, is downregulated upon the loss of the enhancer in both independent deletions, and 4 additional genes are also downregulated in both deletion lines, a secondary effect of the loss of Ivl, as concluded by comparing to the Ivl KO mice. We thus conclude that Ivl is the primary target gene of the 923 enhancer and establish a 923-Ivl regulatory module.

2020-10-30 | GSE158869 | GEO

ATAC-sequencing data for 923 enhancer deletion newborn mouse keratinocytes

Project description:We examined the ATAC-seq chromatin profiles of epidermis from newborn CRISPR-edited mice that have the 923 enhancer located within the Epidermial Differentiation Complex deleted. We examined two independent deletion lines, 923del and 923large, homozygous mutants, as well as wild type mice. We find overall there are not many differences in chromatin accessibility upon the loss of the 923 enhancer, though there are a few peaks of less accessible DNA within the EDC and more accessible DNA just outside the EDC.

2020-10-30 | GSE158868 | GEO

ATAC-sequencing data for 923 enhancer deletion newborn mouse keratinocytes

Project description:ATAC-sequencing data for 923 enhancer deletion newborn mouse keratinocytes

| PRJNA667800 | ENA

923 enhancer deletion newborn mouse

Project description:This SuperSeries is composed of the SubSeries listed below.

2020-10-30 | GSE158870 | GEO

Gene expression analysis of Oxacilin resistance in Stapyloccoccus aureus strains: 923 and V3

Project description:The study aims to identify genes associated with oxacilin resistance. Staphylococcus aureus USA300 (also referred as 923) is used as reference strain through the whole study.

2011-04-08 | GSE26258 | GEO

Gene expression analysis of Oxacilin resistance in Stapyloccoccus aureus strains: 923 and V3

Project description:The study aims to identify genes associated with oxacilin resistance. Staphylococcus aureus USA300 (also referred as 923) is used as reference strain through the whole study. 10 arrays total.

2011-04-08 | E-GEOD-26258 | biostudies-arrayexpress

Staphylococcus aureus subsp. aureus 923

Project description:Staphylococcus aureus subsp. aureus 923 Genome sequencing

| PRJNA80757 | ENA

Escherichia coli K1 strain:923

Project description:Escherichia coli K1 strain:923 Genome sequencing

| PRJNA257955 | ENA

Allele specific deletion of enhancer clusters within mouse F1 embryonic stem cells

Project description:We provide data from several targeted deletions of transcriptional enhancer clusters within mouse F1 embryonic stem (ES) cells. We targeted these regions for deletion with CRISPR/Cas9 genome editing tools. We demonstrate through heterozygous enhancer cluster deletion and allele specific RNA-seq that enhancer clusters differ in their regulatory activity as the magnitude of the observed change in transcription upon enhancer cluster deletion varies greatly.

2016-11-18 | GSE79313 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data