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Expression data from 2-week and 2-month-old mouse testes extracted from wild-type (WT), Sf1:Cre,Prkar1afl/fl (prKO), Amh:Cre,Prkar1afl/fl (srKO), Cyp11a1:Cre,Prkar1afl/fl (lrKO).

ABSTRACT: Expression data from 2-week and 2-month-old mouse testes extracted from wild-type (WT), Sf1:Cre,Prkar1afl/fl (prKO), Amh:Cre,Prkar1afl/fl (srKO), Cyp11a1:Cre,Prkar1afl/fl (lrKO).

PROVIDER: PRJNA667826 | ENA |

REPOSITORIES: ENA

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Expression data from 2-week and 2-month-old mouse testes extracted from wild-type (WT), Sf1:Cre,Prkar1afl/fl (prKO), Amh:Cre,Prkar1afl/fl (srKO), Cyp11a1:Cre,Prkar1afl/fl (lrKO).

Project description:Prkar1a encodes the regulatory subunit R1a of the proteine kinase A. Prkar1a ablation in the testis results in profound alterations of tissue homeostasis leading to tumor development and infertility. We used microarrays to analyze gene expression in response to Prkar1a gene ablation in testicular somatic cells (derived from SF1+ cells) (prKO model), in Sertoli cells (sKO model) or in Leydig cells (lrKO model) in 2-week and 2-month-old mouse testes.

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Atp4b-Cre;Cdh1(fl/fl);Kras(LSL-G12D/+);Trp53(fl/fl);Rosa26(LSL-YFP/LSL-YFP) mouse stomach vs. Atp4b-Cre;Cdh1(fl/+);Kras(LSL-G12D/+);Trp53(fl/fl);Rosa26(LSL-YFP/LSL-YFP) mouse stomach microarray

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2018-05-01 | E-MTAB-5833 | biostudies-arrayexpress

Single Cell RNA Sequencing of WT and Cdh5-cre Myct1 fl/fl Endothelium

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Transcriptional profiling of E14.5 control and Tbr2 fl/fl;Foxg1::Cre cortices

Project description:The abscence of TBR2 gene in human leads to microcephaly. This condition is mimicked by the specific ablation of the murine gene in developing cerebral cortex. Herein we compared gene expression in control and Tbr2 cKO in E14.5 cerebral cortices. This approach represents a useful tool to identify the molecular mechanisms at the basis of the phenotype. 6 samples, 3x Tbr2 +/+;Foxg1::Cre (control) and 3x Tbr2 fl/fl;Foxg1::Cre

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Microarrays analysis of RNA isolated from 7days-Sertoli cell culture of 14 day-old AMH-Cre/WT and WT/WT C57BL/6J mouse testes

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Gene expression in IRfl/fl Cre- and IRfl/fl Cre+ mice

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Gene expression profile of HSCs from Angptl2fl/fl or Cdh5-Cre;Angptl2fl/fl mice

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