Project description:To understand ketoconazole resistance mechanism in M. restricta, we investigated differentially expressed genes in the azole resistant isolates using transcriptome profile. Transcriptomes of ketoconazole susceptible and resistant M. restricta cells in the absence and precence of ketoconazole were compared and analyzed by RNA sequencing.
Project description:To understand the overall effect of the virus on fungal host, we compared the transcriptomes between virus-infected and virus-cured M. restricta strain by using RNA-Seq.
