Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcriptomic screen to identify genes regulated by dSET2 in Drosophila third-instar larval nervous system

ABSTRACT: Transcriptomic screen to identify genes regulated by dSET2 in Drosophila third-instar larval nervous system

PROVIDER: PRJNA680561 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Transcriptomic screen to identify genes regulated by IP3R in Drosophila third-instar larval nervous system

Project description:Transcriptomic screen to identify genes regulated by IP3R in Drosophila third-instar larval nervous system

| PRJNA431574 | ENA

Transcriptomic screen to identify genes regulated by IP3R in Drosophila third-instar larval nervous system

Project description:Organisms need to co-ordinate growth with development particularly in the context of nutrient availability. Thus, multiple ways have evolved to survive extrinsic nutrient deprivation during development. In the holometabolous insect Drosophila, growth occurs during larval development. Larvae are therefore critically dependent on nutritional inputs for pupariation. Post critical weight however, they pupariate even when starved. How nutrient availability is coupled to the internal metabolic state for the decision to pupariate in not well understood and needs better understanding. Wild type larvae, when subjected to nutrient deprivation as mid-third instar larvae, pupariate and also emerge as adults, even though smaller than normally fed ones (Jayakumar et al., 2016; Megha and Hasan, 2017). A recent study (Jayakumar et al., 2016) identified a neuronal circuit that enables wild-type larvae to survive protein deprivation and pupariate. IP3R function in a subset of glutamatergic neurons is a crucial part of the circuit. However, the cellular role of IP3R in these neurons is not understood. In Drosophila neurons, the IP3R causes and facilitates store-operated calcium entry (Chakraborty et al., 2016; Venkiteswaran and Hasan, 2009). Thus it is likely, that the IP3R also regulates expression of genes that regulate this phenomenon. In this study, we have compared the gene expression profiles of control and itpr knockdown larval brains to identify genes that act downstream of the IP3R to regulate pupariation under nutrition stress.

2019-03-01 | GSE109637 | GEO

Expression profile of third instar larval salivary gland tissue

Project description:We use mRNA-seq to transcriptionally profile larval salivary gland tissue from Drosophila third instar larvae. These data provide insights into tissue physiology and can be used to identify tissue specific transcripts.

2011-10-18 | GSE33017 | GEO

Expression profile of third instar larval fat body and midgut tissues

2010-11-02 | GSE25025 | GEO

Transcriptome analysis of control (y w) and Paip1 mutant third instar larval wing imaginal discs

Project description:We report the genome-wide RNA profiling of third instar larval wing imaginal discs upon Paip1 mutation

2023-07-31 | GSE146531 | GEO

Expression profile of third instar larval fat body and midgut tissues

Project description:We use mRNA-seq to transcriptionally profile larval fat body and midgut tissues from Drosophila third instar larvae. These data provide insights into tissue physiology and can be used to identify tissue specific transcripts. Fat bodies from wandering third instar larvae were dissected from ~50 male larvae and gonads were removed to eliminate contaminating transctips from the gonads. Larval midguts were dissected from ~50 wandering third instar larvae. Larval tissues were removed to Graces unsupplemented medium on ice prior to RNA extraction with TRIzol reagent. mRNA-seq samples were prepared from 5ug of total RNA and subject to Illumina based sequencing.

2010-11-02 | E-GEOD-25025 | biostudies-arrayexpress

Pho and Ph, H3K27me3 and Engrailed ChIP-seq data in PRE-deleted third instar Drosophila larval brains and disks and 4C-seq data in the third instar larval brains and disks

Project description:Genome-wide binding profile of PcG proteins- Pho and Ph, H3K27me3 and Engrailed in Drosophila third instar larval brains and disks, in duplicate, using Illumina HiSeq 2500. The sequence reads that passed quality filters were analyzed.

2016-09-24 | GSE77341 | GEO

Transcriptomic screen to identify genes regulated by dSET2 in Drosophila third-instar larval nervous system

Project description:Gene expression changes in neurons are primarily thought to occur via activity driven transcription of immediate-early genes (Chen et al., 2016). Little notice is given to how intracellular Ca2+ changes downstream of myriad signaling pathways affects neuronal gene expression. We recently identified a set of genes whose expression requires IP3R/Ca2+ signals in larval neurons (Jayakumar et al., 2018). This work studies how IP3R/Ca2+ signals regulate changes in gene expression, critical to growth and development, through the histone methyltransferase dSET2. In this study we investigate how IP3R and dSET2 regulate a common set of developmentally significant genes to enable the larval to pupal transition on a protein deprived diet.

2020-11-25 | GSE162094 | GEO

Drosophila melanogaster female late third instar larval gonads single-cell RNA-Seq (scRNA-Seq) profiling

Project description:The larval ovary is made up of multiple cell types including germ cells and somatic cells. The diversity of cell types and transcriptional regulation is not fully understood. To get single cell resolution of larval ovary regulation, we generated single-cell RNA expression profiles (scRNA-Seq) from late third instar larval ovaries of a reference Drosophila melanogaster genotype w[1118].

2019-02-01 | GSE125948 | GEO

Transcriptomic analysis of wild-type and amos mutant D. melanogaster third-instar larval antennal discs and adult antennae

Project description:Comparative transcriptomic analysis of Drosophila melanogaster third-instar larval antennal discs and adult antennae from wild-type animals and amos mutant animals.

2021-12-13 | GSE190696 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data